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Author Topic: Ancient west Eurasian ancestry in southern and eastern Africa 2013
Explorador
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quote:
Originally posted by Swenet:

quote:
Originally posted by The Explorer:
Cite the text (Pagani et al. 2012) that
mentions "SLC45A2", fuckhead monkey.

You now realize that you phucked up when your
glaring obliviousness to the matters being
discussed led you to confuse my mention of SLC45A2
for a mistaken identity with SLC24A5 on my part.
In a desperate bid to safe face and hide your
glaring blunder, you're now moving the goal post
to whether SLC45A2 was singled out and
specifically articulated in Pagani's text. Filthy
lying ass pig, didn't I tell your filthy ass to
stop lying so much?

Ok, Pagani et al.'s text does not mention SLC45A2 at all. That renders you a lying sucker of a stupid monkey.

quote:


quote:
Originally posted by The Explorer:
You've confused Pagani et al.'s application of
"looked at" in the text for this self-interjected
moronic substitution

Lying ass pig, they referenced a 2009 paper which
has a section dedicated to the exact same
pigmentation genes that were of interest to
Pagani et al. Do your struggling neurones imagine
the footnote is sitting there for decoration
purposes? What is it doing there if not serving
as a reference to point their readership to the
genes they themselves had the samples tested for?

Speak up, troll!

Of course, the footnote number is there for the benefit of the reader, so that the reader can track down what "other genes" they are referring to. But that is not what you said that raised eyebrows, fuckhead queen.

Even if Pagani et al. themselves referred to said material to get an idea of what these genes were, they would have still had to familiarize themselves with the actual locations of those genes before they actually sequenced the sites of interest. That's just common sense. They would not therefore be "looking for" the sites; they'd just go right to the sites of interest and examine them accordingly. As such, when the authors noted "looked at" the other genes, they simply meant that they took them (other genes) into consideration, which you comically bungled up and mistook it for your own silly conception that their invocation of "looked at" must signify their "looking at literature first to identify which genes they should be looking ‘’for’’" (your words). LOL, you are such a dense bonehead.

quote:

quote:
Originally posted by The Explorer:
"caught red handed" in this piece, in
which "derived SLC24A5 was selected for in a
tropical environment" is nowhere to be found
outside of your stunted head

...and then the lying ass troll goes on to
re-confirm its shaky interpretation that Pagani
state that SLC24A5 got selected in the Ethiopian
Cushitic-Semitic speakers because of its light
skin associated features.

These are of course your usual silly paraphrasing crap as opposed to my exact words, but in any event, saying that "SLC24A5 got selected in the Ethiopian Cushitic-Semitic speakers" is not the same thing as "derived SLC24A5 was selected for in a tropical environment", now is it?

Nor is saying that the authors identified skin pigmentation as the likely phenotypic trait of this selection, my words, is not the same thing as "derived SLC24A5 was selected for in a tropical environment".

The selection does not have to be a response to the environment, which in this case, happens to be a tropically-situated one. Of course, you'd know this if you were actually clued in what was mentioned in the paper, and how genetics works, rather than manufacturing quotes just to score a point.

quote:

You're stumped by 1) the
fact that the implied populations are living in
highly inconducive intense UV environments

As evidenced by what? Quotes, not dumb misinformed paraphrases.

quote:

2) that
there are no traces of other pigmentation genes
in Semitic-Cushitic speakers (despite their
inferred ancient presence) and 3) that derived
SLC24A5 in the other Ethiopian populations did
not undergo selection.

Again evidences for these crazy accusations that only you seem to be clued in on. And again, just quotes, no misinformed paraphrase.

I did, however, chime in on the first two issues of your "three point" wimpy accusations, and there is clear evidence thereof, that you are stumped crazy, like the stupid monkey you are, on what was actually related about those two issues.

Any one with a slight nerve activity above you, which says a lot since you have none at all, can figure out that your nutty accusations and what was actually said are worlds apart. [Cool]

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IronLion
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quote:
Originally posted by The Explorer:
quote:
Originally posted by Ass-ion:

Ass-plorer is mest up by himself, for himself, with himself...

Ass-ion still has its paper-lion fuckhead up his fat Haile-Selassie worshiping ass, forcing hot-air to channel from the ass-hole to the pot-mouth, which is why stuff (as cited) come out of the pot-orifice that make less and less sense with each blurt.
What is this gibberish above? Demented nah? [Big Grin]

By the way Superfly, I thought you went back to writing your phucked up blog? [Razz]

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Explorador
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What blogs did you write again, Haile Selassie's ass-licking fuckhead?

--------------------
The Complete Picture of the Past tells Us what Not to Repeat

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zarahan aka Enrique Cardova
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Tukler says:
Now a decade after her publication
geneticists don't have to come out
up front and say North Africans are
white Caucasian. They just have to
include Maca-Meyer in their list of
sources.

If they don't take her to task for
using Caucasian then they agree with
her usage.

Dialectic is stronger than explicit.


Rolling "the Cheikh," Doc Ben, Xyyman,
and Zarahan all into one; so-called
generalized or undifferentiated AFRICAN
AMHs step across the Bab el Mendeb, stay a
minute, step back across and voila! here's
your Caucasian Africa(n). Nevermind whiteness,
fleshless lips, rather long but paperthin noses,
and multi-colored eyes and hair developing in a
Arabian Peninsula or SW Asia essentially the same
environmentally etc as NE Africa was at that epoch.


lol.. Amen brother... Now if only more folk would
grasp what you have written and catch on to the
game they are playing...

--------------------
Note: I am not an "Egyptologist" as claimed by some still bitter, defeated, trolls creating fake profiles and posts elsewhere. Hapless losers, you still fail. My output of hard data debunking racist nonsense has actually INCREASED since you began..

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the lioness,
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but who is saying, in these time periods it was across Bab el Mendeb rather than sinai ?
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Elijah The Tishbite
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I come back here and this maniacal trolling is still going on. These DNA studies are only as good as the samples and methods used, compare this study to others done on South Africans and check for similarities, smh
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IronLion
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quote:
Originally posted by The Explorer:
What blogs did you write again, Haile Selassie's ass-licking fuckhead?

Phucked up bytch

Phucked up blog.

Superfly, fly back to your shyt-hole blog... [Big Grin]

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Swenet
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quote:
Originally posted by The Explorer:
Ok, Pagani et al.'s text does not mention
SLC45A2 at all.

Like the sick troll that you are, you're now
structurally lying your way out of your phuckups.
Filty lying ass pig, cite where I said that
Pagani et al mention SLC45A2 explicitly in their
text, rather than simply having identified it as
one of the genes implicated in what they meant
when they said ''we also looked at other
genes
associated with pigmentation in
Europe''. While you're at it, explain how your
persistent trolling in regards to this tenacious
lie of yours, rectifies your earlier fabricated
lie that my mention of the gene was an accident.

quote:
Originally posted by The Explorer:
As such, when the authors noted "looked
at" the other genes, they simply meant that they
took them (other genes) into consideration

Cognitively challenged lying ass troll, how is the
highlighted inconsistent with what I said,
namely, that the authors consulted the
aforementioned source? What would have preceded
this ''taking into consideration'', if not getting
updated on prospect genes, which they could then
test their samples for?

quote:
Originally posted by The Explorer:
but in any event, saying that "SLC24A5 got
selected in the Ethiopian Cushitic-Semitic
speakers" is not the same thing as "derived
SLC24A5 was selected for in a tropical
environment", now is it?

Unless these people aren't actually tropical
populations, it isn't going to matter whether you
explicitly said they were equatorial, you phuchin'
jackass. You said skin pigmentation is a ''likely
phenotypic candidate of this selection'' (end
quote) in populations who reside at an equatorial
lattitude.

quote:
Originally posted by The Explorer:
And again, just quotes, no misinformed
paraphrase

You're now asking me to quote where you
were stumped? You're such a cognitively impaired
sack of sh!t, LMAO. How is someone supposed to
quote a non-verbal state of mind (being stumped),
you filthy dumbass pig? Then again, making such
braindead logically impracticable requests is
right up your alley, recalling earlier crackhead
requests you made, such as ''cite the accuracies
in Kefi 2005''.

Explain the following specifics under your
crackpot view that derived SLC24A5 got selected
for in the sampled Cushitic-Semitic speakers due
to its light skin associated expression:

You're stumped by 1) the fact that the implied
populations are living in highly inconducive
intense UV environments 2) that there are no
traces of other pigmentation genes in Semitic-
Cushitic speakers (despite their inferred ancient
presence) and 3) that derived SLC24A5 in the
other Ethiopian populations did not undergo
selection.

--Swenet

When you’ve mustered up the balls to do so, try
tackling the following inconvenient facts as
well, will ya? I have more ass whooping in store
for your lying ass:

quote:
Originally posted by Swenet:
quote:
Originally posted by The Explorer:
Go ahead and ask many more times, the answer
doesn't change

Of course it won’t, and the reason is none other
than the fact that you can’t answer it without
inserting girly giggle accompanied
unsubstantiated claims that the Sri Lankan skin
pigmentation state of affairs bolsters your
non-existent case! For the fourth time it’s
observed that you’re scared sh!tless to address
what is being shoved in your face, with more than
tail between legs amygdala triggered non-replies:

Lying ass troll, the Sri Lankan samples had an
excess of SLC24A5, and a severe deficit of
SLC45A2. Explain this under your crackpot theory
that a severe minority of SLC24A5 correlated
genes testify to an indigenous origin of this
gene.

--Swenet

Just thought I’d ’remind’ you that you ran away
from this, here, too:

quote:
Originally posted by Swenet:
quote:
Originally posted by The Explorer:
I thought I already clued in your stupid
monkey ass that if there were no other skin
pigmentation genes in Ethiopians

You’re such a phuckin’ low IQ, dumbass, charlatan.
Is your bum ass saying that the Ethiopian sample
implicated here wouldn’t have had additional skin
pigmentation genes, had, let’s say, derived
SLC45A2 been found in them? Get to work, fraud:

If not negative selection, explain why no
other skin pigmentation genes were found in the
Ethiopian population

--Swenet


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Explorador
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quote:
Originally posted by Swenet:

Like the sick troll that you are, you're now
structurally lying your way out of your phuckups.
Filty lying ass pig, cite where I said that
Pagani et al mention SLC45A2 explicitly in their
text, rather than simply having identified it as
one of the genes implicated in what they meant
when they said ''we also looked at other
genes
associated with pigmentation in
Europe''. While you're at it, explain how your
persistent trolling in regards to this tenacious
lie of yours, rectifies your earlier fabricated
lie that my mention of the gene was an accident.

That's just it, fuckhead queen. You are a moron of a unique kind for focusing on a gene that wasn't even mentioned in the paper.

quote:


Cognitively challenged lying ass troll, how is the
highlighted inconsistent with what I said

fuckhead queen, you do realize by this absentminded begging, that you are in effect saying that you don't know how to read this text, don't you:

"when the authors noted "looked at" the other genes, they simply meant that they took them (other genes) into consideration, which you comically bungled up and mistook it for your own silly conception that their invocation of "looked at" must signify their "looking at literature first to identify which genes they should be looking ‘’for’’" (your words). LOL, you are such a dense bonehead."

That's why you were instructed to let your care-taker do all your reading, but you are about as terribly handicapped at taking instructions as you are reading.

quote:

Unless these people aren't actually tropical
populations, it isn't going to matter whether you
explicitly said they were equatorial, you phuchin'
jackass.

Other than fuckhead crackpots, who else would be intellectually inept enough to say that quoting information correctly does not matter?

On top of that, you make another stupid claim about Ethiopians not "actually tropical populations". Your mental ineptness just gets worse by the minute...and you wishfully accuse me of being the stumped one, LOL.

quote:
You said skin pigmentation is a ''likely
phenotypic candidate of this selection'' (end
quote) in populations who reside at an equatorial
lattitude.

Let's stick to what I actually said:

the paper only identifies skin pigmentation as the likely phenotypic candidate of this selection.

I bet that the stupid monkey will scratch its head in trying to figure out the difference between what I just cited, and what the moron claims I said.

quote:
You're now asking me to quote where you
were stumped?

You retarded monkey. You were instructed to provide "evidence" for your crazy accusations. Naturally, that would mean first quoting (not silly misinformed paraphrases) me, and then demonstrating where I went wrong, jackass!

Somebody should sufficiently pad your small basement room for your own safety, not to leave out a straitjacket. [Big Grin]

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Explorador
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Come to think of it, when you said...

quote:
Originally posted by Swenet:

You're such a cognitively impaired
sack of sh!t, LMAO. How is someone supposed to
quote a non-verbal state of mind (being stumped),
you filthy dumbass pig?

Rather than whining about my requests, which were actually monumentally kind to your accusations, considering how illogical they were, it is your own accusations that you should be perplexed about. Given that you are tacitly saying your accusation speaks to "a non-verbal state of mind", how the heck then can you discern "a non-verbal state of mind", when you have no "verbal basis" for it? Are you into some kind of a supernatural witchcraft crap?
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IronLion
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quote:
Originally posted by The Explorer:
buzzzz...buzzzzz.... I am a supernatural witchcraft crap!

Yes so says Ass-plorer the endangered Superfly, the crap eater...

 -

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Swenet
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quote:
Originally posted by The Explorer:
You are a moron of a unique kind for
focusing on a gene that wasn't even mentioned in
the paper.

Sick lying ass troll, this is the third
time that you're running away from addressing
this segment of the discussion:

Like the sick troll that you are, you're now
structurally lying your way out of your phuckups.
Filty lying ass pig, cite where I said that
Pagani et al mention SLC45A2 explicitly in their
text, rather than simply having identified it as
one of the genes implicated in what they meant
when they said ''we also looked at other
genes
associated with pigmentation in
Europe''. While you're at it, explain how your
persistent trolling in regards to this tenacious
lie of yours, rectifies your earlier fabricated
lie that my mention of the gene was an accident.

--Swenet

quote:
Originally posted by The Explorer:
when the authors noted "looked at" the
other genes, they simply meant that they took
them (other genes) into consideration, which you
comically bungled up and mistook it for your own
silly conception that their invocation of "looked
at" must signify their "looking at literature
first to identify which genes they should be
looking ‘’for’’

You phuchin' troll, this is the 2nd time that
you're desperately running away from this segment
of the discussion. Explain how ''taking into
consideration'', in this context, is supposedly an
endeavour separated from ''consulting the
literature'', to make sense of the non-existent
dichotomy between ''taking into consideration''
and ''consulting the literature'', that you're
desperately hoping will catch on. Surely there
must be an explanation for why your crippled
sh!t stained brains are attempting to discredit my
interpretation of that Pagani et al citation
with what can only be described as another way of
saying what I said.

quote:
Originally posted by The Explorer:
Other than fuckhead crackpots, who else
would be intellectually inept enough to say that
quoting information correctly does not matter?

Lying ass pig, it is obvious that you're not only
running away from what I'm telling you, but that
you apparently on the other side of the 99,9% of
the educated public who know the difference
between a paraphrase and a verbatim quote:

Unless these people aren't actually tropical
populations, it isn't going to matter whether you
explicitly said they were equatorial, you phuchin'
jackass.

--Swenet

quote:
Originally posted by The Explorer:
Let's stick to what I actually said:
the paper only identifies skin pigmentation as
the likely phenotypic candidate of this selection.

Which brings us back to the fact that the paper
says light skin got selected for in the case of
Europeans, and makes no such explicit case
for Ethiopians. Which then brings us back to the
fact that what you proclaim is a view of the
authors, is really your own retarded claim,
hiding behind someone else’s authority. Which
brings us back to the fact that it was none other
than your own retarded ass that said that light
skin got selected for in populations who reside
in the tropics.

quote:
Originally posted by The Explorer:
You were instructed to provide "evidence"
for your crazy accusations. Naturally, that would
mean first quoting (not silly misinformed
paraphrases) me, and then demonstrating where I
went wrong, jackass!

Filthy pig, your stupidity has no bounds! You
asked someone to reproduce, out of a textual
exchange, records of something that’s inherently
non-verbal. Even worse: you then go on a full
blown super stumped discourse, talking about how,
if there was no record of this apparent fact in
the said textual exchange, your demented neurones
find it a real enigma that it could have been
discerned in other ways:

Given that you are tacitly saying your
accusation speaks to "a non-verbal state of
mind", how the heck then can you discern "a
non-verbal state of mind"

--The Explorer

According to this crippled reasoning, I must not
know for a fact that you're alive, simply because
there is no explicit record of this in the textual
exchanges in this thread! Do you have any idea
how insanely retarded your barely functioning
neurones must be, to be sending impulses to
your crack besmirched lips that it's okay to be
talking such unearthly stupid smack? Get your
microcephalic head looked at, son!

When you’ve mustered up the balls to do so, try
tackling the following inconvenient facts as
well, will ya? I have more ass whooping in store
for your lying ass:

quote:
Originally posted by Swenet:
quote:
Originally posted by Swenet:
quote:
Originally posted by The Explorer:
Go ahead and ask many more times, the answer
doesn't change

Of course it won’t, and the reason is none other
than the fact that you can’t answer it without
inserting girly giggle accompanied
unsubstantiated claims that the Sri Lankan skin
pigmentation state of affairs bolsters your
non-existent case! For the fourth time it’s
observed that you’re scared sh!tless to address
what is being shoved in your face, with more than
tail between legs amygdala triggered non-replies:

Lying ass troll, the Sri Lankan samples had an
excess of SLC24A5, and a severe deficit of
SLC45A2. Explain this under your crackpot theory
that a severe minority of SLC24A5 correlated
genes testify to an indigenous origin of this
gene.

--Swenet

Just thought I’d ’remind’ you that you ran away
from this, here, too:

quote:
Originally posted by Swenet:
quote:
Originally posted by The Explorer:
I thought I already clued in your stupid
monkey ass that if there were no other skin
pigmentation genes in Ethiopians

You’re such a phuckin’ low IQ, dumbass, charlatan.
Is your bum ass saying that the Ethiopian sample
implicated here wouldn’t have had additional skin
pigmentation genes, had, let’s say, derived
SLC45A2 been found in them? Get to work, fraud:

If not negative selection, explain why no
other skin pigmentation genes were found in the
Ethiopian population

--Swenet



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Explorador
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quote:
Originally posted by Swenet:

Sick lying ass troll, this is the third
time that you're running away from addressing
this segment of the discussion:

Like the sick troll that you are, you're now
structurally lying your way out of your phuckups.
Filty lying ass pig, cite where I said that
Pagani et al mention SLC45A2 explicitly in their
text, rather than simply having identified it as
one of the genes implicated in what they meant
when they said ''we also looked at other
genes
associated with pigmentation in
Europe''. While you're at it, explain how your
persistent trolling in regards to this tenacious
lie of yours, rectifies your earlier fabricated
lie that my mention of the gene was an accident.

--Swenet

You've only managed to confirm the astute observation that you are a moron with no peers. Who else reads "other genes" as specifically "SLC45A2" but a numbskull such as yourself?

Just like a quick sand, the more you try to justify your profound stupidity, the more you sink.

quote:
Lying ass pig, it is obvious that you're not only
running away from what I'm telling you, but that
you apparently on the other side of the 99,9% of
the educated public who know the difference
between a paraphrase and a verbatim quote

It's no rocket science that the meaning of the word "lying" is alien to you, as are a number of other simple terms. This is what you can expect from fuckheads who can't tell "taking into consideration" apart from "consulting the literature". In a clear contrast to you, my reply is premised on firsthand evidence--an actual quote, which is hard to lie about after the fact, even though that never stops you [as I said, you are a unique moron like that].

You are not mentally competent to paraphrase just yet; leave that to thinking-people, my fuckhead queen.

quote:
Which brings us back to the fact that the paper
says light skin got selected for in the case of
Europeans, and makes no such explicit case
for Ethiopians.

Utter silliness--you were already spoon fed about the only biological function (skin pigmentation) the paper identifies in the real world, and in association, how a marker serving as gene flow (what you've been vainly wishing for) works; go back and read. Oh wait; you have trouble with reading!

Comprehending genetics is far out. You have a more pressing problem: Seek reading 101 first.

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Swenet
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quote:
Originally posted by The Explorer:
Who else reads "other genes" as specifically
"SLC45A2" but a numbskull such as yourself?

You're lying again, filthy pig. If not, cite,
without relapsing to your amygdala triggered habit
of fleeing the scene, where I even remotely said
something to the effect that SLC45A2 itself was
the text's ''other genes''.

quote:
Originally posted by The Explorer:
This is what you can expect from fuckheads
who can't tell "taking into consideration" apart
from "consulting the literature".

Produce this imaginary, cooked up, account where
''taking into consideration'' was conflated with
''consulting the literature'' in any context,
other than the one implied here, where the
''taking into consideration'' of genes would have
happened by way of ''consulting the literature'',
wherein these genes are described.

quote:
Originally posted by The Explorer:
Utter silliness--you were already spoon
fed about the only biological function (skin
pigmentation) the paper identifies in the real
world

Dumb sack a sh!t, in addition to coding for skin
color, SLC24A5 has also been found to code for
eye color, among other things. Explain this under
your cuckoo, sh!t stained fairy tale that Pagani
et al's reference to ''biological function'' here
should refer exclusively to SLC24A5's skin color
associated expression. Then, when you're done
performing this pre-defeated undertaking, explain
to me how light skin color got selected for in an
equatorial population.

What your dumbass ''forgot'' to address in the
midst of the thrashing you've been submitted
to:


quote:
Originally posted by Swenet:
quote:
Originally posted by The Explorer:
when the authors noted "looked at" the
other genes, they simply meant that they took
them (other genes) into consideration, which you
comically bungled up and mistook it for your own
silly conception that their invocation of "looked
at" must signify their "looking at literature
first to identify which genes they should be
looking ‘’for’’

You phuchin' troll, this is the 2nd time that
you're desperately running away from this segment
of the discussion. Explain how ''taking into
consideration'', in this context, is supposedly an
endeavour separated from ''consulting the
literature'', to make sense of the non-existent
dichotomy between ''taking into consideration''
and ''consulting the literature'', that you're
desperately hoping will catch on. Surely there
must be an explanation for why your crippled
sh!t stained brains are attempting to discredit my
interpretation of that Pagani et al citation
with what can only be described as another way of
saying what I said.

quote:
Originally posted by The Explorer:
Other than fuckhead crackpots, who else
would be intellectually inept enough to say that
quoting information correctly does not matter?

Lying ass pig, it is obvious that you're not only
running away from what I'm telling you, but that
you apparently on the other side of the 99,9% of
the educated public who know the difference
between a paraphrase and a verbatim quote:

Unless these people aren't actually tropical
populations, it isn't going to matter whether you
explicitly said they were equatorial, you phuchin'
jackass.

--Swenet

quote:
Originally posted by The Explorer:
Let's stick to what I actually said:
the paper only identifies skin pigmentation as
the likely phenotypic candidate of this selection.

Which brings us back to the fact that the paper
says light skin got selected for in the case of
Europeans, and makes no such explicit case
for Ethiopians. Which then brings us back to the
fact that what you proclaim is a view of the
authors, is really your own retarded claim,
hiding behind someone else’s authority. Which
brings us back to the fact that it was none other
than your own retarded ass that said that light
skin got selected for in populations who reside
in the tropics.

quote:
Originally posted by The Explorer:
You were instructed to provide "evidence"
for your crazy accusations. Naturally, that would
mean first quoting (not silly misinformed
paraphrases) me, and then demonstrating where I
went wrong, jackass!

Filthy pig, your stupidity has no bounds! You
asked someone to reproduce, out of a textual
exchange, records of something that’s inherently
non-verbal. Even worse: you then go on a full
blown super stumped discourse, talking about how,
if there was no record of this apparent fact in
the said textual exchange, your demented neurones
find it a real enigma that it could have been
discerned in other ways:

Given that you are tacitly saying your
accusation speaks to "a non-verbal state of
mind", how the heck then can you discern "a
non-verbal state of mind"

--The Explorer

According to this crippled reasoning, I must not
know for a fact that you're alive, simply because
there is no explicit record of this in the textual
exchanges in this thread! Do you have any idea
how insanely retarded your barely functioning
neurones must be, to be sending impulses to
your crack besmirched lips that it's okay to be
talking such unearthly stupid smack? Get your
microcephalic head looked at, son!

When you’ve mustered up the balls to do so, try
tackling the following inconvenient facts as
well, will ya? I have more ass whooping in store
for your lying ass:

quote:
Originally posted by Swenet:
quote:
Originally posted by Swenet:
quote:
Originally posted by The Explorer:
Go ahead and ask many more times, the answer
doesn't change

Of course it won’t, and the reason is none other
than the fact that you can’t answer it without
inserting girly giggle accompanied
unsubstantiated claims that the Sri Lankan skin
pigmentation state of affairs bolsters your
non-existent case! For the fourth time it’s
observed that you’re scared sh!tless to address
what is being shoved in your face, with more than
tail between legs amygdala triggered non-replies:

Lying ass troll, the Sri Lankan samples had an
excess of SLC24A5, and a severe deficit of
SLC45A2. Explain this under your crackpot theory
that a severe minority of SLC24A5 correlated
genes testify to an indigenous origin of this
gene.

--Swenet

Just thought I’d ’remind’ you that you ran away
from this, here, too:

quote:
Originally posted by Swenet:
quote:
Originally posted by The Explorer:
I thought I already clued in your stupid
monkey ass that if there were no other skin
pigmentation genes in Ethiopians

You’re such a phuckin’ low IQ, dumbass, charlatan.
Is your bum ass saying that the Ethiopian sample
implicated here wouldn’t have had additional skin
pigmentation genes, had, let’s say, derived
SLC45A2 been found in them? Get to work, fraud:

If not negative selection, explain why no
other skin pigmentation genes were found in the
Ethiopian population

--Swenet




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quote:
Originally posted by Swenet:

You're lying again, filthy pig. If not, cite,
without relapsing to your amygdala triggered habit
of fleeing the scene, where I even remotely said
something to the effect that SLC45A2 itself was
the text's ''other genes''.

skanky piece of trash, on top of being reading-retarded, are you now suffering from Alzheimer's, so that you can't remember highlighting "other genes" in your remark, as a justification for your obsession over an allele that is not even mentioned in Pagani et al.'s paper? What will be the next misfortune of your careless simple-minded lying spree: gouging your eyes out? LOL

quote:
Dumb sack a sh!t, in addition to coding for skin
color, SLC24A5 has also been found to code for
eye color, among other things.

Where does Pagani et al.'s (2012) text make a reference to "eye color"? Cite it, princess dufus. You are not on the same planet as either the study in question or this discussion.
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quote:
Originally posted by IronLion:
quote:
Originally posted by The Explorer:
buzzzz...buzzzzz.... I love supernatural witchcraft crap!

Yes so says Ass-plorer the endangered Superfly, the crap eater...

 -


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the lioness,
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 -
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quote:
Originally posted by the lioness:
 -

George Washington

Black Caucasian ....


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quote:
Originally posted by IronLion:
quote:
Originally posted by the lioness:
..
 -
Dorthea Duchess, pricess of Denmark, Duchess of Prussia (1504-1547)

Gee, IronLion has fu cked me again!

quote:
Originally posted by IronLion:
Lion killing Lioneseee [Big Grin]

2000years before now...
 -



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quote:
Originally posted by The Explorer:
are you now suffering from Alzheimer's, so that
you can't remember highlighting "other genes" in
your remark

What I can't remember, lying ass troll, is the
existence of neurodegenerative conditions where
patients feel compelled to distort an observation
as simple as ''SLC45A2 was just one of several
genes
implicated in Pagani et al's text'', into
your lying ass allegation that ''other genes''
was said to refer ''specifically'' to SLC45A2:

Who else reads "other genes" as specifically
"SLC45A2"
but a numbskull such as yourself?

--The Explorer

quote:
Originally posted by The Explorer:
Where does Pagani et al.'s (2012) text make a
reference to "eye color"?

Dumb sack a sh!t with ADHD attention span, my
invocation of other expressions of the SLC24A5
gene was a direct response to your earlier
fabricated mumbo jumbo claptrap that other
expressions of the gene are ''fictitious'', and
your psychologically self-comforting fairy tale
that the ''biological function'' of SLC24A5,
referred to in Pagani's text, necessarily refers
to it's skin color related expression, in the case
of Cushitic-Semitic speaking Ethiopians. Where is
the evidence for such a pre-conceived, entirely
made up, self-serving reading of the Pagani
passage?

Utter silliness--you were already spoon
fed about the only biological function (skin
pigmentation) the paper identifies in the real
world

--The Explorer

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quote:
Originally posted by Swenet:

What I can't remember, lying ass troll, is the
existence of neurodegenerative conditions where
patients feel compelled to distort an observation
as simple as ''SLC45A2 was just one of several
genes
implicated in Pagani et al's text'', into
your lying ass allegation that ''other genes''
was said to refer ''specifically'' to SLC45A2

LOL, so your dumb monkey ass now figures that by saying "just one of severals genes implicated" as supposed--misguided--substitute for "other genes", you'll somehow placate the fact that you made SLC45A2 the focus of a text which says absolutely nothing about the allele? Well, you thought wrong, again, shithead.


quote:
Dumb sack a sh!t with ADHD attention span, my
invocation of other expressions of the SLC24A5
gene was a direct response to your earlier
fabricated mumbo jumbo claptrap that other
expressions of the gene are ''fictitious''

Then missy, to put it another way, you were bamboozled by--and "directly responded" to--one of your reading-retarded screw ups. Calling you out for ascribing imaginary stories to Pagani & co. is not synonymous with "other expressions of the gene are ''fictitious''".

quote:
and
your psychologically self-comforting fairy tale
that the ''biological function'' of SLC24A5,
referred to in Pagani's text, necessarily refers
to it's skin color related expression, in the case
of Cushitic-Semitic speaking Ethiopians. Where is
the evidence for such a pre-conceived, entirely
made up, self-serving reading of the Pagani
passage?

Try this recap from page 1, reading-retarded donkey:

"Of the fourteen 40-SNP windows observed with a Z-score > 2, we noted one that contained SLC24A5 (MIM 113750). This gene is a major contributor to the pigmentation differences between Africans and Europeans and a strong candidate for positive selection in Europe.4"

"To further investigate the effect of admixture on the **genetic landscape of skin pigmentation** in Ethiopia, we also looked at other genes associated with pigmentation in Europe; however, none were found in our outlier regions."

"SLC24A5 was within the top 5% of selection signals, whereas the gene was not detected as an outlier in the other groups of Ethiopians. The unusual history of this gene was further supported by the presence of the derived A allele of the SNP rs1834640, associated with the light skin pigmentation of Europeans and western Asians..."

"This putative migration from the Levant to Ethiopia, which is also supported by linguistic evidence, may have carried the derived western Eurasian allele of SLC24A5, which is associated with light skin pigmentation."

The paper identifies skin pigmentation as phenotypic trait of the allele, not once but several times over. This has not deterred your thick monkey skull from saying that it's just my interpretation, just so your fairy tale unspecified "biological function" can have a companion. - Explorer, 12 August, 2013

PS: What's the deal with Selassie's ass-kissing pussy-cat. Just an observation: ass-ion's pink undies get in a bunch every time you get thrashed. Are you two love birds, or what?

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quote:
Originally posted by The Explorer:
LOL, so your dumb monkey ass now figures
that by saying "just one of severals genes
implicated" as supposed--misguided--substitute for
"other genes", you'll somehow placate the fact
that you made SLC45A2 the focus of a text which
says absolutely nothing about the allele?

Lying ass filthy pig, your permanently stumped
neurones were caught red handed going from your
earlier crack induced rant about a supposed
mix-up of SLC45A2 and SLC24A5 on my part, to your
current super stumped rant on how explicit
references on SLC45A2 are supposedly missing from
the Pagani text. All the while, your severely
handicapped brains are still at a loss as to how
to deal with footnote 46 (you know, the footnote
your lying ass went to great lengths to scratch
out of the undoctored text it originally appeared
in)--whether to cope with it by running away from
it, or by simply acting like it doesn't exist.
Filthy liar, SLC45A2, among other selection
candidate pigmentation genes, is explicitly
mentioned in the paper associated with footnote
46. No amount of lying and buying time with your
snaky deceptive ploys about what is, or isn't
explicitly discussed in Pagani et al 2012 is
going to change that fact.

quote:
Originally posted by The Explorer:
Calling you out for ascribing imaginary
stories to Pagani & co. is not synonymous with
"other expressions of the gene are
''fictitious''".

Filthy pig, if not an outright pathological lie,
told by a lying pig with an axe to grind, explain
how your earlier insistence that non skin color
associated expressions of SLC24A5 are ''ficticious''
should be read.

quote:
Originally posted by The Explorer:
Try this recap from page 1, reading-
retarded donkey:

Dumbass troll, none of their excerpts pertaining
to SLC24A5 based selection in Europeans
automatically make it so that the same
expression underwent selection in Cushitic-
Semitic speakers in Ethiopia. That's precisely
why your cognitively challenged ass had to be
schooled earlier on the fact that they conducted
their tests to picture the impact that the
different Ethiopian environments had on their
foreign ancestral component. Yet, being the slow,
clueless phuck that you are, you apparently still
don't get it. Delirious claptrap ravings about
Europeans aside, man up for once, deadbeat
lying ass pig, and explain, taking into account
the just administered embarrassing reprimand that
Ethiopians aren't subject to the same high
latitude/low UV selective pressures as Northern
Europeans, how your pre-defeated attempts to
invoke European based SLC24A5 selection
automatically advances your retarded claim that
the same gene expression underwent the same
(locally non-existent) selective pressures in
equatorial Ethiopia.

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quote:
Originally posted by Swenet:

Lying ass filthy pig, your permanently stumped
neurones were caught red handed going from your
earlier crack induced rant about a supposed
mix-up of SLC45A2 and SLC24A5 on my part, to your
current super stumped rant on how explicit
references on SLC45A2 are supposedly missing from
the Pagani text. All the while, your severely
handicapped brains are still at a loss as to how
to deal with footnote 46 (you know, the footnote
your lying ass went to great lengths to scratch
out of the undoctored text it originally appeared
in)--whether to cope with it by running away from
it, or by simply acting like it doesn't exist.
Filthy liar, SLC45A2, among other selection
candidate pigmentation genes, is explicitly
mentioned in the paper associated with footnote
46. No amount of lying and buying time with your
snaky deceptive ploys about what is, or isn't
explicitly discussed in Pagani et al 2012 is
going to change that

Moaning and fussing hysterically like the deranged monkey you are about how you were called out or in what form it supposedly took from one occasion to another will not wish away the fact that you made SLC45A2 the focal point of a text that does not mention it at all.

The footnote? Simply there for reader reference, not what you abused it for: to excuse your buffoonish mistaking of "looked at" in the text to mean "looking at literature first, blah blah". We've already been through this, numbnuts.


quote:


quote:
Originally posted by The Explorer:

Calling you out for ascribing imaginary
stories to Pagani & co. is not synonymous with
"other expressions of the gene are
''fictitious''".

Filthy pig, if not an outright pathological lie,
told by a lying pig with an axe to grind, explain
how your earlier insistence that non skin color
associated expressions of SLC24A5 are ''ficticious''
should be read.

What you cited above is all there's to know, silly monkey, and is only made more relevant by what you just babbled.
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quote:
Originally posted by The Explorer:
The footnote? Simply there for reader reference,
not what you abused it for

Filthy lying ass troll, in the midst of all your
lies, distortions, manipulations and logical
fallacies, did you really think your meaningless
pussyfooting around segments of my posts that
aren't even focal points to what I'm saying, are
going to go unnoticed? Fumbling, incompetent,
asswipe, your deceptive ploy where you talk about
everything other than the focal point of the
excerpt you're pretending to address, aside,
explain this under your brainless cuckoo theory
that SLC45A2 was not among the ''other genes''
Pagani et al used in their analysis and tested the
Ethiopian samples were tested for:

All the while, your severely
handicapped brains are still at a loss as to how
to deal with footnote 46 (you know, the footnote
your lying ass went to great lengths to scratch
out of the undoctored text it originally appeared
in)--whether to cope with it by running away from
it, or by simply acting like it doesn't exist.
Filthy liar, SLC45A2, among other selection
candidate pigmentation genes, is explicitly
mentioned in the paper associated with footnote
46. No amount of lying and buying time with your
snaky deceptive ploys about what is, or isn't
explicitly discussed in Pagani et al 2012 is
going to change that.

--Swenet

quote:
Originally posted by The Explorer:
What you cited above is all there's to know,
silly monkey, and is only made more relevant by
what you just babbled.

Chemically imbalanced unintelligible rants aside,
one cannot help but notice the cosmic gap in
between your retarded description of the other
factual expressions of SLC24A5 as ''ficticious''
and what the scientific literature has to say
about the non skin color related phenotypes the
gene codes for. Would one be correct in resolving
this discrepancy between fact and your dogmatic
denial as that you're a pathologically lying ass
pig, led by faith-based self-comforting
inclinations, rather than readily observable
reality?

This is the 8th point of contention that you're
now going on record, running away from, like the
little amygdala-led wussy that you are:


quote:
Originally posted by The Explorer:
quote:
Originally posted by Swenet:
quote:
Originally posted by The Explorer:
Try this recap from page 1, reading-
retarded donkey:

Dumbass troll, none of their excerpts pertaining
to SLC24A5 based selection in Europeans
automatically make it so that the same
expression underwent selection in Cushitic-
Semitic speakers in Ethiopia. That's precisely
why your cognitively challenged ass had to be
schooled earlier on the fact that they conducted
their tests to picture the impact that the
different Ethiopian environments had on their
foreign ancestral component. Yet, being the slow,
clueless phuck that you are, you apparently still
don't get it. Delirious claptrap ravings about
Europeans aside, man up for once, deadbeat
lying ass pig, and explain, taking into account
the just administered embarrassing reprimand that
Ethiopians aren't subject to the same high
latitude/low UV selective pressures as Northern
Europeans, how your pre-defeated attempts to
invoke European based SLC24A5 selection
automatically advances your retarded claim that
the same gene expression underwent the same
(locally non-existent) selective pressures in
equatorial Ethiopia.

(....crickets.....)
*I, Explorer, am such a panic stricken b!tch.
When I'm not lying, distorting or manipulating, I
run away from others' posts all the time. I make
up for my lack of being unable to keep up by
playing make believe. I simply profess to be
adamant that my being on the run somehow doesn't
mean I got my ass handed to me and use other
self-deceptive tricks that inadvertently only
broadcast how out of touch I am with regular
folk reality!*


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Explorador
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quote:
Originally posted by Swenet:

Filthy lying ass troll, in the midst of all your
lies, distortions, manipulations and logical
fallacies, did you really think your meaningless
pussyfooting around segments of my posts that
aren't even focal points to what I'm saying, are
going to go unnoticed? Fumbling, incompetent,
asswipe, your deceptive ploy where you talk about
everything other than the focal point of the
excerpt you're pretending to address, aside,
explain this under your brainless cuckoo theory
that SLC45A2 was not among the ''other genes''
Pagani et al used in their analysis and tested the
Ethiopian samples were tested for

You mean another meaningless focal point (just like the meaningless emphasis on SLC45A2) of your dumb rabid monkey ass about what some supposed referenced-study mentions, which is neither the focal point of Pagani et al.'s text or this discussion. Go pick some lice, that's all you are good for, LOL.

quote:
quote:
Originally posted by The Explorer:
What you cited above is all there's to know,
silly monkey, and is only made more relevant by
what you just babbled.

Chemically imbalanced unintelligible rants aside
The unintelligible rant you are complaining about comes from no other but thyself, silly:

other factual expressions of SLC24A5 as ''ficticious'' - authored by swenet [Smile]

You'll not track it back to any other quote (sans your nutty misinformed paraphrases) other than your own.

quote:


gene codes for. Would one be correct in resolving
this discrepancy between fact and your dogmatic
denial as that you're a pathologically lying ass
pig, led by faith-based self-comforting
inclinations, rather than readily observable
reality?

"Faith-based" like your clueless nutty accusations about being "stumped":

You're stumped by 1) the
fact that the implied populations are living in
highly inconducive intense UV environments 2) that
there are no traces of other pigmentation genes
in Semitic-Cushitic speakers (despite their
inferred ancient presence) and 3) that derived
SLC24A5 in the other Ethiopian populations did
not undergo selection.
- swenet

Apparently the only way you feel like you can get away from the gargantuan mess of a flop that represents your "contribution" to this discussion, is to either bizarrely obsess yourself with things that are totally irrelevant to Pagani et al.'s text and this discussion (e.g. some undefined "non-Skin pigmentation" biological function not mentioned by Pagani et al, SLC45A2 not mentioned by Pagani et al, etc), or just make crazy harebrained accusations that amount to half baked voodooism behind a computer screen.

quote:
(....crickets.....)
*I, Explorer, am such a panic stricken b!tch.
When I'm not lying, distorting or manipulating, I
run away from others' posts all the time. I make
up for my lack of being unable to keep up by
playing make believe. I simply profess to be
adamant that my being on the run somehow doesn't
mean I got my ass handed to me and use other
self-deceptive tricks that inadvertently only
broadcast how out of touch I am with regular
folk reality!*

stupid monkey scratch, stupid monkey sleep, stupid monkey eat, and stupid monkey poop. That's your worth in a nutshell, if you get my drift.
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Synopsis of what transpired, starting with this partial recap from page 1:


The easing up of skin eumelanin in San hunter-gatherers has generally been attributed to local evolution in lower UV radiation environments they frequent, as opposed to the result of gene flow. In the Ethiopian samples, on the other hand, the presence of the "derived" variant of the SLC24A5 gene was peculiar in that it was not found in tandem with other "skin-pigmentation" affiliated genes whose distribution generally paralleled that of the "derived" SLC24A5 variant, particularly in Europeans. Hence, "frequency" in itself is not a sufficient enough indicator for ascribing a single-source origin in the form of a "non-African" origin. - Extract ends

From blog entry, "What Ethiopian Genetic Diversity—Really—Reveals!", May 15, 2013:

This [SLC24A5] gene, in its derived form, which is said to be under positive selection in "lightly" pigmented populations, was implicated in the San, who as noted above, tend to generally be isolated, and culturally-conservative hunter-gatherers. "Derived" variants of other pigmentation-associated genes were also cited, with respect to the San([5]). It is questionable that this gene is serving as a "non-African" marker in the San. The same issue actually surfaces with regards to its presence in Ethiopian groups:

Secondly:

Given that SLC24A5 is one of the most highly differentiated genes between African and European populations, we then looked for other highly differentiated genes among the outlier windows, but found none...

To further investigate the effect of admixture on the genetic landscape of skin pigmentation in Ethiopia, we also looked at other genes associated with pigmentation in Europe; however, none were found in our outlier regions.


If this gene, in its "derived" form, was essentially serving as a "non-African" marker in the Ethiopians, then one would expect that other "derived" skin-pigmentation markers would have been introduced along with the SLC24A5 allele, by the foreign "non-African" group(s) that is supposed to have been the source. Skin pigmentation is the byproduct of the consortial work of a number of distinct genes, and so, it's highly unlikely that a "derived" SLC24A5 allele would be introduced without other accompanying skin-pigmentation genes.

No less, it's highly unlikely that only the derived "SLC24A5" allele would survive from a foreign "non-African" source, in a population for which the allele's presence is "potentially disadvantageous", as the authors note, on grounds of the kind of UV-radiation intensive environment they generally reside. Likewise, if as the authors note, the presence of the derived SLC24A5 allele in Ethiopians may be attributable to "socially"-promoted selection, then one would think that other skin-pigmentation genes, which would have accompanied the SLC24A5 allele in an introduction by a foreign "non-African" source, would have likely also survived in some capacity or another, so as to serve the same role that the SLC24A5 may be serving. --Extract ends

As any rational person will glean from these notes, the issues raised undoubtedly emerge from a scientific and objective groundwork. - The Explorer, June 30, 2013

These notes naturally speak to the arguments put forth by Pagani et al., but they set off mindless hysteria in the fuckhead queen called 'swenet'...

who starts babbling about some undefined "non-skin pigmentation" related "biological function" of the derived SLC24A5 variant supposedly introduced to Ethiopians via "gene flow"...

To this, the idiot was informed that a marker serving as "gene flow" would be introduced "as is", and as such, one that is under selective pressure, will continue to have that selective attribute. From there, it boils down to whether the selective trait is advantageous or deleterious--and to what degree--to the "receiving" population, which will subsequently decide the fate of an allele. The "receiving" population doesn't get to cherry pick which trait to pick and which to discard at a conference table; that's not how nature works to swenet's dismay.

Furthermore, the knucklehead doesn't understand that SLC24A5 having a "different biological function" in Ethiopians from that of an alleged external source, actually weakens the claim for "gene flow", and only reinforces the point I'm making above.

My objection to the idiot's obsession over said "different biological function" that is presumably "non-skin pigmentation related", is that it is immaterial to Pagani et al.'s case, since they make no mention of such a "biological function", other than "skin pigmentation" as the phenotypic trait associated with the SLC24A5 variant. This was turned upside down by the fuckhead queen to mean, that "non-skin pigmentation" related expressions of SLC24A5 gene are "fictitious".

I also clearly note in the blog passages above that:

Skin pigmentation is the byproduct of the consortial work of a number of distinct genes - from the blog

So, it is not unheard of for a population to have a skin pigmentation allele that resembles that of populations which are usually identified with said allele, and yet, have other skin pigmentation alleles that are different from said populations. The derived variant of SLC24A5 similar to the type present in Europe and "southwest Asia" can be present in Ethiopians, yet other alleles that typically accompany the variant in the said regions can be absent in Ethiopians. As such, even if SLC24A5 has a phenotypic trait that is generally disadvantageous in the tropics, by its lonesome, it is not going to have as profound an impact on skin pigmentation as it allegedly does in say, Europeans...

which brings us to the question of why then, there seems to be indication (as shown in the Z-scores) that a derived variant is "selected for" in Ethiopians. Pagani et al., apparently working with their "gene flow" theory, posit that it could be the byproduct of "socially" channeled "selection", like say, "sexual selection". I've already laid out the coherency difficulties which inflict that composite theorizing.

While the "social factor" is a plausible scenario, unlike Pagani et al., I posit that the allele could have been selected initially for a different environment, on the African continent itself (the sub-tropical Sahara), in the ancestral populations of Ethiopians in question.

fuckhead queen also turned upside down, my arguments to this end; instead fuckhead queen says "I" am making a case for "a selection of light skin pigmentation in the tropical environment", and asks me why "other genes" (skin pigmentation) typically found in Europe and "southwest Asia", were not found in Ethiopians. I told the fuckhead queen, it's because Ethiopians have their own skin pigmentation genes, otherwise they would be colorless.

By this silly question, what the fuckhead queen was really trying to say, is that other skin pigmentation alleles vanished into extinction, while the SLC24A5 variant stayed. But the fuckhead realizes that this runs into one of the problems I already identified: that it makes no sense for SLC24A5 to stick around, given the identified (in the text) phenotypic trait associated with skin pigmentation, while other skin pigmentation alleles serving a similar purpose, simply vanished. This forced the fuckhead queen to look to some other, presumably a "non-skin pigmentation" related "biological function" of the gene, that Pagani et al.'s text makes no mention of. The fuckhead queen was thereafter called out for fictitiously ascribing said unspecified "biological function" to Pagani et al.'s text, but fuckhead queen translated this to mean, "other biological functions of SLC24A5 are fictitious". [Big Grin]

The fuckhead queen was even forced to refer to "eye color" as this supposed "non-skin pigmentation" related "biological function" at one point. That led to an obvious dead end, when the fuckhead queen was asked to cite Pagani et al.'s piece making a case of that nature.

My theory takes into account the plausibility that the "derived" SLC24A5 variant may have been initially selected for in a different African environment, but because it merely contributed to the skin tone continuum seen in said Ethiopians, as opposed to having a decisive role, SLC24A5 variant managed to survive the UV environment of the tropics. This is how my theory takes into account, the "social factor" that Pagani et al were speaking of, in an entirely different context.

You see, the ancestors of said Ethiopians living in sub-tropical African environment north of the equator may have undergone some skin pigmentation relaxation, initially as a response to the said sub-tropical environment, but not enough to have gone to the extreme relaxations seen in Europe, for instance. As such, their skin pigmentation relaxation was perhaps not extreme enough to make their survival in the tropical African environment unbearable. This will adequately account for why SlC24A5 derived variant happens to appear in Ethiopians at substantial frequencies, while other skin pigmentation alleles generally associated with Europeans do not.

The fuckhead queen proceeds to ask me why there is frequency disparity between major Cushitic-Semitic Ethiopian groups and the Omotic and Nilotic Ethiopians. To it's puzzlement, the fuckhead queen was thereof informed that it must be reflective of the different bio-histories of said groups. [BTW, I give details of these distinct bio-histories in the blog entry cited]

As if that was not bizarre enough, the fuckhead queen cites from a different study, that is totally irrelevant to Pagani et al.'s text or this discussion: the fuckhead queen cites from a study comparing Sri Lankans to several samples, including those from Europe. It is from here, that SLC45A2 was introduced into this discussion. The fuckhead queen's motive for this citation, was supposedly to show me that SLC24A5 was found in Sri Lankans along with SLC45A2, which must therefore mean that they only attained SLC24A5 from Europeans, and henceforth, supposedly refute what I said about the Ethiopian case, which no less, resembles nothing like the Sri Lankan case.

The only [unintended] thing the Sri Lankan case managed to do, is give even more fodder to my argument, since even that study--as irrelevant as it was--showed that it was SLC45A2 rather than SLC24A5 that proved to sufficiently differentiate European samples and the Sri Lankan counterparts; SLC24A5 was relatively weak in performing that role. What this means, is that between the two skin pigmentation variants, SLC45A2 would have served better as a marker of European ancestry than would SLC24A2, if such a case were to hypothetically be entertained. Simply put, SLC24A5 has a wider distribution, and hence, more generic.

Running out of ideas to con a way out of this mess of a fiasco that missy created, fuckhead queen decides to take a crack at nutty accusations about "being stumped", presumably by some "three" bulleted points. Asked for evidence, in the form of quotes, the fuckhead queen says that it is from a "non-verbal" analysis, which is beyond comical, because the only way to know anything about me, is from what I write in the thread.

fuckhead queen would have to either see me to read my body language perhaps, which any sane person knows is out of the question, or have supernatural powers to read minds afar from behind a computer screen. fuckhead queen instead compares this bizarre accusation with the prospect of "knowing that I exist", but presumably me denying this. Of course, the fuckhead queen would know I exist, only because I happen to post here and elsewhere. But try telling something that very simple to princess dufus.

From here, everything only becomes repetitive, as fuckhead queen tries to salvage whatever's left of that tattered ego from merciless defeat. Going in circles, with wimpy posts about how I supposedly did the fuckhead queen wrong, left something said (usually pure crap) unadressed or how I "lied" about some post or another, is what fuckhead queen usually does after humiliating defeat in every discussion. [Smile]

For the finer details, spectators need to just turn to the first page, but this sums up what happened. [Wink]

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Swenet
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quote:
Originally posted by The Explorer:
You mean another meaningless focal point (just
like the meaningless emphasis on SLC45A2) of your
dumb rabid monkey ass about what some supposed
referenced-study mentions, which is neither the
focal point of Pagani et al.'s text or this
discussion.


Dumb, lying ass, vegetative pig, without reverting
to your snaky pathological habit of running away
from the facts, how is the paper associated with
citation number 46 (and the skin pigmentation genes
mentioned therein), which Pagani et al formulate in
the following manner, not the focal point of what
Pagani et al mean when they say ''other genes''?

''other genes associated with pigmentation
in Europe 46
[...]''


quote:
Originally posted by The Explorer:
The unintelligible rant you are complaining
about comes from no other but thyself, silly:

This brainless attempt to disguise your inability
to save your hide in the face of being made out
for the fraudulent liar you are aside, one cannot
help but notice the cosmic gap in between your
retarded description of the other factual
expressions of SLC24A5 as ''fictitious'' and what
the scientific literature has to say about the
non skin color related phenotypes the gene codes
for. Would one be correct in resolving this
discrepancy between fact and your dogmatic denial
as that you're a pathologically lying ass pig,
led by faith-based self-comforting inclinations,
rather than readily observable reality?

 -

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Explorador
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quote:
Originally posted by Swenet:

how is the paper associated with
citation number 46 (and the skin pigmentation genes
mentioned therein), which Pagani et al formulate in
the following manner, not the focal point of what
Pagani et al mean when they say ''other genes''?

Easy, queen of skank: SLC45A2 was not mentioned in the text you want to wish it in, that's how irrelevant it is.

The real question is, how many more times must your retarded dry ass be clued in on this. Endless times, that's what, because you are fuckhead queen. [Smile]

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Explorador
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quote:
Originally posted by The Explorer:

which brings us to the question of why then, there seems to be indication (as shown in the Z-scores) that a derived variant is "selected for" in Ethiopians.

I'd like to add another thing about these Z-scores, with regards to technicalities. Given the cut-off points picked by Pagani et al., there is no telling of whether say, any skin pigmentation alleles outside of SLC24A5, which may resemble variants of Europeans or "southwest Asians", could have had neutral-seeming occurrences across the tropical African populations analyzed; the only thing is, such occurrences will neither point to a drifting out (of deleterious alleles) event nor a natural selection event (for biologically or socially advantageous alleles), if that makes any sense or is even possible. Pagani et al.'s readers are only informed about the regions they deemed outliers, of which said alleles (outside of SLC24A5) would not have been a part. In any event, the prospect seems very unlikely given that Pagani et al. did not capitalize on it in any capacity, to bolster their "gene flow" theories. And in such a hypothetical scenario, even if they did, they'd run into a problem similar to the one outlined in my blog notes, with regards to the prospects of negative drift or natural selection.
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Swenet
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quote:
Originally posted by The Explorer:
SLC45A2 was not mentioned in the
text
you want to wish it in, that's how
irrelevant it is.

Lying ass fraud, you're quite uncreative with your
repetitive, shaky-legged, amygdala triggered non-
replies to my very simple question:

how is the paper associated with citation
number 46 (and the skin pigmentation genes
mentioned therein), not the focal point of what
Pagani et al mean when they say ''other genes''?

--Swenet

quote:
Originally posted by The Explorer:
I'd like to add another thing about these
Z-scores

Dumbass, your uninformed input is not needed,
your dumbass is arguing from a position of
cluelessness. You will not post evidence that
Ethiopians have derived SLC45A2, because you can't.
Your worthless super stumped pussyfooting speculations
are already pre-defeated by the literature.

quote:
Originally posted by The Explorer:
Given the cut-off points picked by Pagani et al.

What would these ''cut-off points'' be?
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Elijah The Tishbite
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This back and forth is boring.........
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Tukuler
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What? Yr actually reading it?

I keep checkin in hopin ta learn sumpin
but I cyaan wade thru all thaa **** even
if a pearl or two might be buried in it.


But slong as they enjoy it
let em carry on, they made this
thread into a series of PMs.

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xyyman
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tru dat!! waste of band width.

--------------------
Without data you are just another person with an opinion - Deming

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Swenet
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Bored? Aint concerned with the next man's
entertainment. You're not contractually obligated
to read anything, nor are forcefully spoon-fed the
''boring'' exchanges that you (for some strange
reason) seem unwilling to tune out of.

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zarahan aka Enrique Cardova
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quote:
Originally posted by The Explorer:
Synopsis of what transpired, starting with this partial recap from page 1:


The easing up of skin eumelanin in San hunter-gatherers has generally been attributed to local evolution in lower UV radiation environments they frequent, as opposed to the result of gene flow. In the Ethiopian samples, on the other hand, the presence of the "derived" variant of the SLC24A5 gene was peculiar in that it was not found in tandem with other "skin-pigmentation" affiliated genes whose distribution generally paralleled that of the "derived" SLC24A5 variant, particularly in Europeans. Hence, "frequency" in itself is not a sufficient enough indicator for ascribing a single-source origin in the form of a "non-African" origin. - Extract ends

From blog entry, "What Ethiopian Genetic Diversity—Really—Reveals!", May 15, 2013:

This [SLC24A5] gene, in its derived form, which is said to be under positive selection in "lightly" pigmented populations, was implicated in the San, who as noted above, tend to generally be isolated, and culturally-conservative hunter-gatherers. "Derived" variants of other pigmentation-associated genes were also cited, with respect to the San([5]). It is questionable that this gene is serving as a "non-African" marker in the San. The same issue actually surfaces with regards to its presence in Ethiopian groups:

Secondly:

Given that SLC24A5 is one of the most highly differentiated genes between African and European populations, we then looked for other highly differentiated genes among the outlier windows, but found none...

To further investigate the effect of admixture on the genetic landscape of skin pigmentation in Ethiopia, we also looked at other genes associated with pigmentation in Europe; however, none were found in our outlier regions.


If this gene, in its "derived" form, was essentially serving as a "non-African" marker in the Ethiopians, then one would expect that other "derived" skin-pigmentation markers would have been introduced along with the SLC24A5 allele, by the foreign "non-African" group(s) that is supposed to have been the source. Skin pigmentation is the byproduct of the consortial work of a number of distinct genes, and so, it's highly unlikely that a "derived" SLC24A5 allele would be introduced without other accompanying skin-pigmentation genes.

No less, it's highly unlikely that only the derived "SLC24A5" allele would survive from a foreign "non-African" source, in a population for which the allele's presence is "potentially disadvantageous", as the authors note, on grounds of the kind of UV-radiation intensive environment they generally reside. Likewise, if as the authors note, the presence of the derived SLC24A5 allele in Ethiopians may be attributable to "socially"-promoted selection, then one would think that other skin-pigmentation genes, which would have accompanied the SLC24A5 allele in an introduction by a foreign "non-African" source, would have likely also survived in some capacity or another, so as to serve the same role that the SLC24A5 may be serving. --Extract ends
.. a marker serving as "gene flow" would be introduced "as is", and as such, one that is under selective pressure, will continue to have that selective attribute. From there, it boils down to whether the selective trait is advantageous or deleterious--and to what degree--to the "receiving" population, which will subsequently decide the fate of an allele. The "receiving" population doesn't get to cherry pick which trait to pick and which to discard at a conference table; that's not how nature works to swenet's dismay.
..

Skin pigmentation is the byproduct of the consortial work of a number of distinct genes - from the blog

So, it is not unheard of for a population to have a skin pigmentation allele that resembles that of populations which are usually identified with said allele, and yet, have other skin pigmentation alleles that are different from said populations. The derived variant of SLC24A5 similar to the type present in Europe and "southwest Asia" can be present in Ethiopians, yet other alleles that typically accompany the variant in the said regions can be absent in Ethiopians. As such, even if SLC24A5 has a phenotypic trait that is generally disadvantageous in the tropics, by its lonesome, it is not going to have as profound an impact on skin pigmentation as it allegedly does in say, Europeans...

which brings us to the question of why then, there seems to be indication (as shown in the Z-scores) that a derived variant is "selected for" in Ethiopians. Pagani et al., apparently working with their "gene flow" theory, posit that it could be the byproduct of "socially" channeled "selection", like say, "sexual selection". I've already laid out the coherency difficulties which inflict that composite theorizing.

While the "social factor" is a plausible scenario, unlike Pagani et al., I posit that the allele could have been selected initially for a different environment, on the African continent itself (the sub-tropical Sahara), in the ancestral populations of Ethiopians in question.

My theory takes into account the plausibility that the "derived" SLC24A5 variant may have been initially selected for in a different African environment, but because it merely contributed to the skin tone continuum seen in said Ethiopians, as opposed to having a decisive role, SLC24A5 variant managed to survive the UV environment of the tropics. This is how my theory takes into account, the "social factor" that Pagani et al were speaking of, in an entirely different context.

You see, the ancestors of said Ethiopians living in sub-tropical African environment north of the equator may have undergone some skin pigmentation relaxation, initially as a response to the said sub-tropical environment, but not enough to have gone to the extreme relaxations seen in Europe, for instance. As such, their skin pigmentation relaxation was perhaps not extreme enough to make their survival in the tropical African environment unbearable. This will adequately account for why SlC24A5 derived variant happens to appear in Ethiopians at substantial frequencies, while other skin pigmentation alleles generally associated with Europeans do not.

Just to clarify here:

^^(1) Under what scenario could the derived SLC24A5 variant
have been selected for? Climate zone variations over log time spans?
Differing micro-clime zones spread over a broad
Saharan/NE African geographic space?

2) Does your approach absolutely reject any outside gene
flow or do you still leave the door open for such,
while holding that the primary pattern of variation
or diversity could well be indigenous, from within
the African continent or the NE African region?

3) On your blog you take issue with Pagani's definitions
of a so-called "African" versus "non-African" component.
Does the use of Yoruba samples as the primary "African"
Exhibit represent a variation of the old "true negro" game,
as you see it?

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Elijah The Tishbite
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quote:
Originally posted by Swenet:
Bored? Aint concerned with the next man's
entertainment. You're not contractually obligated
to read anything, nor are forcefully spoon-fed the
''boring'' exchanges that you (for some strange
reason) seem unwilling to tune out of.

I fail to see what you're both arguing about, are you arguing that this gene came out or is it indigenous? If it came from outside please explain how Somalis, who were tested in that genetic study by Pangani are darker than Ethiopians despite having nearly the same amount of genetic admixture as Ethiopians. I really do care for this back and forth name calling and trolling, you both sound like punks for real.
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Explorador
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quote:
Originally posted by Swenet:

Dumbass, your uninformed input is not needed,
your dumbass is arguing from a position of
cluelessness.

You must be basing this "uninformed input" on some creepy "non-verbal state of mind" supernatural intuition, rather than unemotional evidence-based premise?

quote:

You will not post evidence that
Ethiopians have derived SLC45A2, because you can't.

LOL, why note the obvious only now...after endless attempts to clue your fuckhead to no avail! If I can't quote Pagani & co. on "Ethiopians having derived SLC45A2", then naturally, a useless skank as yourself doesn't stand a chance to do better.
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Explorador
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quote:
Originally posted by zarahan- aka Enrique Cardova:

quote:
Originally posted by The Explorer:

Synopsis of what transpired, starting with this partial recap from page 1:


The easing up of skin eumelanin in San hunter-gatherers has generally been attributed to local evolution in lower UV radiation environments they frequent, as opposed to the result of gene flow. In the Ethiopian samples, on the other hand, the presence of the "derived" variant of the SLC24A5 gene was peculiar in that it was not found in tandem with other "skin-pigmentation" affiliated genes whose distribution generally paralleled that of the "derived" SLC24A5 variant, particularly in Europeans. Hence, "frequency" in itself is not a sufficient enough indicator for ascribing a single-source origin in the form of a "non-African" origin. - Extract ends

From blog entry, "What Ethiopian Genetic Diversity—Really—Reveals!", May 15, 2013:

This [SLC24A5] gene, in its derived form, which is said to be under positive selection in "lightly" pigmented populations, was implicated in the San, who as noted above, tend to generally be isolated, and culturally-conservative hunter-gatherers. "Derived" variants of other pigmentation-associated genes were also cited, with respect to the San([5]). It is questionable that this gene is serving as a "non-African" marker in the San. The same issue actually surfaces with regards to its presence in Ethiopian groups:

Secondly:

Given that SLC24A5 is one of the most highly differentiated genes between African and European populations, we then looked for other highly differentiated genes among the outlier windows, but found none...

To further investigate the effect of admixture on the genetic landscape of skin pigmentation in Ethiopia, we also looked at other genes associated with pigmentation in Europe; however, none were found in our outlier regions.


If this gene, in its "derived" form, was essentially serving as a "non-African" marker in the Ethiopians, then one would expect that other "derived" skin-pigmentation markers would have been introduced along with the SLC24A5 allele, by the foreign "non-African" group(s) that is supposed to have been the source. Skin pigmentation is the byproduct of the consortial work of a number of distinct genes, and so, it's highly unlikely that a "derived" SLC24A5 allele would be introduced without other accompanying skin-pigmentation genes.

No less, it's highly unlikely that only the derived "SLC24A5" allele would survive from a foreign "non-African" source, in a population for which the allele's presence is "potentially disadvantageous", as the authors note, on grounds of the kind of UV-radiation intensive environment they generally reside. Likewise, if as the authors note, the presence of the derived SLC24A5 allele in Ethiopians may be attributable to "socially"-promoted selection, then one would think that other skin-pigmentation genes, which would have accompanied the SLC24A5 allele in an introduction by a foreign "non-African" source, would have likely also survived in some capacity or another, so as to serve the same role that the SLC24A5 may be serving. --Extract ends
.. a marker serving as "gene flow" would be introduced "as is", and as such, one that is under selective pressure, will continue to have that selective attribute. From there, it boils down to whether the selective trait is advantageous or deleterious--and to what degree--to the "receiving" population, which will subsequently decide the fate of an allele. The "receiving" population doesn't get to cherry pick which trait to pick and which to discard at a conference table; that's not how nature works to swenet's dismay.
..

Skin pigmentation is the byproduct of the consortial work of a number of distinct genes - from the blog

So, it is not unheard of for a population to have a skin pigmentation allele that resembles that of populations which are usually identified with said allele, and yet, have other skin pigmentation alleles that are different from said populations. The derived variant of SLC24A5 similar to the type present in Europe and "southwest Asia" can be present in Ethiopians, yet other alleles that typically accompany the variant in the said regions can be absent in Ethiopians. As such, even if SLC24A5 has a phenotypic trait that is generally disadvantageous in the tropics, by its lonesome, it is not going to have as profound an impact on skin pigmentation as it allegedly does in say, Europeans...

which brings us to the question of why then, there seems to be indication (as shown in the Z-scores) that a derived variant is "selected for" in Ethiopians. Pagani et al., apparently working with their "gene flow" theory, posit that it could be the byproduct of "socially" channeled "selection", like say, "sexual selection". I've already laid out the coherency difficulties which inflict that composite theorizing.

While the "social factor" is a plausible scenario, unlike Pagani et al., I posit that the allele could have been selected initially for a different environment, on the African continent itself (the sub-tropical Sahara), in the ancestral populations of Ethiopians in question.

My theory takes into account the plausibility that the "derived" SLC24A5 variant may have been initially selected for in a different African environment, but because it merely contributed to the skin tone continuum seen in said Ethiopians, as opposed to having a decisive role, SLC24A5 variant managed to survive the UV environment of the tropics. This is how my theory takes into account, the "social factor" that Pagani et al were speaking of, in an entirely different context.

You see, the ancestors of said Ethiopians living in sub-tropical African environment north of the equator may have undergone some skin pigmentation relaxation, initially as a response to the said sub-tropical environment, but not enough to have gone to the extreme relaxations seen in Europe, for instance. As such, their skin pigmentation relaxation was perhaps not extreme enough to make their survival in the tropical African environment unbearable. This will adequately account for why SlC24A5 derived variant happens to appear in Ethiopians at substantial frequencies, while other skin pigmentation alleles generally associated with Europeans do not.

Just to clarify here:

^^(1) Under what scenario could the derived SLC24A5 variant
have been selected for? Climate zone variations over log time spans?
Differing micro-clime zones spread over a broad
Saharan/NE African geographic space?

This has already been addressed in the very paragraph you cited. See above: initial selection in the sub-tropical region of the Sahara. Unless the spinning orientation of the Earth has dramatically shifted (as opposed to minor wobbles) time and again, such things should not change much over time.

Skin pigmentation content correlates with UV radiation intensity, not heat, or general weather.

quote:

2) Does your approach absolutely reject any outside gene
flow or do you still leave the door open for such,
while holding that the primary pattern of variation
or diversity could well be indigenous, from within
the African continent or the NE African region?

In scientific theory, there generally are no absolutes. If you are referring to SLC24A5, then I'm saying the evidence put before me does not point to "gene flow from outside"; that's what I'm saying. Rather, it points to an autochthonous origin scenario.

quote:


3) On your blog you take issue with Pagani's definitions
of a so-called "African" versus "non-African" component.
Does the use of Yoruba samples as the primary "African"
Exhibit represent a variation of the old "true negro" game,
as you see it?

It's analogous to it. [Wink]
Posts: 7516 | From: Somewhere on Earth | Registered: Jan 2008  |  IP: Logged | Report this post to a Moderator
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quote:
Originally posted by .Charlie Bass.:

I fail to see what you're both arguing about

It is a self-responsibility to read preceding material. If ones so chooses not to do that, then that's on said individual, who should not be in a position to whine to others about not knowing what's going on. At any rate, I went through the trouble of writing out a synopsis--particularly for the lazy--of what the commotion in this thread is about, as briefly as possible. I tried to simplify the jargon in that synopsis for the benefit of those who might find some of the genetic stuff a little consuming.

quote:
I really do care for this back and forth name calling and trolling, you both sound like punks for real.
...and you have now become a part of this club of punks.
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Swenet
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You're repeatedly logging in and clicking on a
thread, solely to repeatedly spam your disapproval
of what is supposed to take place on a forum. This
is odd behaviour in and of itself. Why would a
grown man repeatedly solicit other men's attention
and lament being a witness of something he himself
is making himself go through?

Then, you call the thread boring, but yet, can't
recall for the life of you what is being discussed.

Then, to top it all off, you criticize people for
their name calling, which you then comically
proceed to self-righteously indulge in yourself
with your own 'insults'.

Your erratic behaviour is puzzling. What is your
closet reason for logging in to repeatedly
express your disapproval, which you then go on
to admit, is totally baseless? You know what, I
don't even want your answer. Just hop off my you
know what, take your see-through 'holier than
thou' masquerade and go play with your friends
over at Dodona, where you're known for routinely
doing the same thing you're now pathetically
trying knock, trying to get brownie points.

quote:
Originally posted by .Charlie Bass.:
I really do care for this back and forth
name calling
and trolling,

quote:
Originally posted by .Charlie Bass.:
you both sound like punks for real.


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I'm on yo ass, boy!

quote:
Originally posted by Swenet:
[QB]
quote:
Originally posted by The Explorer:
SLC45A2 was not mentioned in the
text
you want to wish it in, that's how
irrelevant it is.

Lying ass fraud, you're quite uncreative with your
repetitive, shaky-legged, amygdala triggered non-
replies to my very simple question:

how is the paper associated with citation
number 46 (and the skin pigmentation genes
mentioned therein), not the focal point of what
Pagani et al mean when they say ''other genes''?

--Swenet

 -

If your balls didn't desert you, like they did the
past hundred times you were asked to address the
above, you can take a stab at addressing these
inconvenient dumpers, that you dogmatically failed
to take into account:

quote:
Originally posted by The Explorer:
See above: initial selection in the sub-tropical
region of the Sahara.

The admixture event dates to 3kya. You're not
going to wish this admixture event away by
assigning Ethiopians a fabricated origin in the
Sahara. The Syria-like genetic component would
still have to become an important genetic
contribution, even within your shitty scenario.
Not to mention, the hard to swallow pill that
this component has an obvious connection to
derived SLC24A5 in Ethiopians, also seems to have
slipped through the gaping holes of your
''Sahara'' figment.

Other than that, I sure would like to see the
pre-defeated piece of evidence that warrants this
misty ''Sahara'' scenario, where the sampled
Cushitic-Speakers are somehow not the descendants
of Axum era equatorial populations, but of some
Northern entity that's solely the product of your
rabid imagination.

Moreover, how does selection on the derived gene
in Ethiopians qualify as a remnant of some
imaginary proto population in the Sahara, when
the other Ethiopians (Omotic speakers), who
derive from the exact same ancestral populations
(they only vary from Cushitic-Semitic speakers in
their amount of Syrian-like ancestry), don't have
excesses of the derived gene?

It would also be nice to see the ecological
specifics you've gathered before you went public
with that claptrap theory, so as to make sure you
wouldn't be making a complete ass out of yourself,
by suggesting that light skin is advantageous in
the Sahara.

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quote:
Originally posted by Swenet:

I'm on yo ass, boy!

Like the mindless Nancy boy fag you are?

quote:
The admixture event dates to 3kya. You're not
going to wish this admixture event away by
assigning Ethiopians a fabricated origin in the
Sahara.

To do that, I'd have to fabricate Ethiopian genetic profiles; thanks for the ass-kissing, but you are venerating me with way more extraordinary powers than I'm capable of. [Smile]

To familiarize with "fabrication", just look no further than your mindlessly parroted 3kya date.

quote:
The Syria-like genetic component would
still have to become an important genetic
contribution, even within your shitty scenario.

"Syria-like" genetic component, LOL; spoken like a true chump with its head up the ass.


quote:
Not to mention, the hard to swallow pill that
this component has an obvious connection to
derived SLC24A5 in Ethiopians, also seems to have
slipped through the gaping holes of your
''Sahara'' figment.

You nailed the "hard to swallow pill" bit of your comically chumpy analysis.

I bet you are just dying to tell us what "obvious connection" the San hunter-gatherer (and indeed other sub-Saharan Africans) marker of the like has to "this component". While at it numbnuts, entertain us with the juicy legendary stories of from which particular Asians the San attained the "derived" OCA2, which they apparently share with "light skin" east Asians.


quote:

It would also be nice to see the ecological
specifics you've gathered before you went public
with that claptrap theory, so as to make sure you
wouldn't be making a complete ass out of yourself,
by suggesting that light skin is advantageous in
the Sahara.

numbnuts, you are confusing a no-brainer for rocket science, because that's how practically stupid you are; the Sahara spans the sub-tropical area. You may confide with early primary school kids to give you a tip on the geography. Forget me; the ass you should be looking out for is you, which you just made a fool of. LOL

PS: Why don't you tell us more about how it is like to be a gullible brainwashed sap who buys into the "forest negro" concept as the true African. It obviously shapes your emotional ideas about Africans, not leaving out the false sense of duty of telling Africans who are true Africans and who aren't.

Posts: 7516 | From: Somewhere on Earth | Registered: Jan 2008  |  IP: Logged | Report this post to a Moderator
Elijah The Tishbite
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quote:
Originally posted by Swenet:
You're repeatedly logging in and clicking on a
thread, solely to repeatedly spam your disapproval
of what is supposed to take place on a forum. This
is odd behaviour in and of itself. Why would a
grown man repeatedly solicit other men's attention
and lament being a witness of something he himself
is making himself go through?

Then, you call the thread boring, but yet, can't
recall for the life of you what is being discussed.

Then, to top it all off, you criticize people for
their name calling, which you then comically
proceed to self-righteously indulge in yourself
with your own 'insults'.

Your erratic behaviour is puzzling. What is your
closet reason for logging in to repeatedly
express your disapproval, which you then go on
to admit, is totally baseless? You know what, I
don't even want your answer. Just hop off my you
know what, take your see-through 'holier than
thou' masquerade and go play with your friends
over at Dodona, where you're known for routinely
doing the same thing you're now pathetically
trying knock, trying to get brownie points.

quote:
Originally posted by .Charlie Bass.:
I really do care for this back and forth
name calling
and trolling,

quote:
Originally posted by .Charlie Bass.:
you both sound like punks for real.


It was a typo I made, but yes, you both do sound like punks agree to disagree and shut up and move on and last like I checked no *STRAIGHT* man would tell another man to suck his you know what so your sexuality is now in question. Funny how nether of you punks responded to my question as it pertained to the topic, smh
Posts: 2595 | From: Vicksburg | Registered: Feb 2006  |  IP: Logged | Report this post to a Moderator
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Charlie the sissy, which question was not already addressed, as it pertained to the ongoing exchanges, not your own diversion?

--------------------
The Complete Picture of the Past tells Us what Not to Repeat

Posts: 7516 | From: Somewhere on Earth | Registered: Jan 2008  |  IP: Logged | Report this post to a Moderator
Elijah The Tishbite
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quote:
Originally posted by The Explorer:
Charlie the sissy, which question was not already addressed, as it pertained to the ongoing exchanges, not your own diversion?

This one

quote:
are you arguing that this gene came out or is it indigenous? If it came from outside please explain how Somalis, who were tested in that genetic study by Pangani are darker than Ethiopians despite having nearly the same amount of genetic admixture as Ethiopians.
Punk sounding people can't read?
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And you are living proof of this punk sounding creep, since after all, your question does not follow from anything I've argued thus far. I'm not making a case for a non-African introduction of the downstream SLC24A5 variant, swenet is.

PS: Charlie, I strongly urge you to reconsider directing your poorly-thought through silly invectives at me, just as I urged that clown swenet to refrain from the same at an earlier time, after having made several attempts to have an adult conversation with the character, which unfortunately fell on the stubborn def ears of a mule. Consequently, I approach the clown as a special case where communication at the human level is futile. So I ask: Do you want to become another such special case? Because if you do, then by all means, continue with the uncultured keyboard thuggery, and I'll make sure you are dealt with at a level you best understand. It's all on you, my friend, but don't say I didn't warn you. [Smile]

--------------------
The Complete Picture of the Past tells Us what Not to Repeat

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Elijah The Tishbite
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lol, I was calling you both clowns for going back and forth and found it funny that one of my topics was linked to, but its all good. lol. You don't have enough brains to come close to annihilating me, even though I've retired at doing this stuff.
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Charlie, you are such a fuckheaded sissy that you cannot tell your ass from your head, and see that you are a bigger clown than anybody for being a prime example of what you're crying like a baby about. On this point, I agree with the other fuckhead (swenet). What has your Mississippi jungle ass offered to begin with, that warrants "annihilating" your trailer trash countryside ass? LOL

Far from retiring, you are a veteran par excellence at being an idiot, who makes a good piñata to be made a complete fool of at white nationalist cult avenues? [Big Grin]

--------------------
The Complete Picture of the Past tells Us what Not to Repeat

Posts: 7516 | From: Somewhere on Earth | Registered: Jan 2008  |  IP: Logged | Report this post to a Moderator
Elijah The Tishbite
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quote:
Originally posted by The Explorer:
Charlie, you are such a fuckheaded sissy that you cannot tell your ass from your head, and see that you are a bigger clown than anybody for being a prime example of what you're crying like a baby about. On this point, I agree with the other fuckhead (swenet). What has your Mississippi jungle ass offered to begin with, that warrants "annihilating" your trailer trash countryside ass? LOL

Far from retiring, you are a veteran par excellence at being an idiot, who makes a good piñata to be made a complete fool of at white nationalist cult avenues? [Big Grin]

You sound like you have PTSD from fighting all of those bad Euros, what has Evil Euro and Horemheb done to you?

I was a vet here in the beginning and put my work in and what I've done to build here stands for itself, I don't have to trade insults with you and thus sound like a punk to prove anything, lol

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Come on buddy: You came at me with your insults, out of nowhere in the misguidedly-disguised form of playing some sort of a "peace-maker". My issue is with just swenet, at this point, as anybody with half a brain knows that I do partake in civil exchanges with those who conduct themselves accordingly. Anyone else who got thrashed thereby invited it upon one self when he/she decided to play the emotional cheerleader and come at me the wrong way. That suggests to me, that you are bad at lying, since you are obviously trying to "prove something", however bad at it you are.
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