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Author Topic: The pre-historic distribution of mitochondrial DNA haplogroup H in Africa and Europe
xyyman
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The distribution of mitochondrial DNA haplogroup H in southern Iberia indicates ancient human genetic exchanges along the western edge of the Mediterranean. - Hernández CL


Idiots need not apply


Abstract
BACKGROUND:
The structure of haplogroup H reveals significant differences between the western and eastern edges of the Mediterranean, as well as between the northern and southern regions. Human populations along the westernmost Mediterranean coasts, which were settled by individuals from two continents separated by a relatively narrow body of water, show the highest frequencies (Ha! HA! Ha! )of mitochondrial haplogroup H. These characteristics permit the analysis of ancient migrations between both shores, which may have occurred via primitive sea crafts and early seafaring. We collected a sample of 750 autochthonous people from the southern Iberian Peninsula (Andalusians from Huelva and Granada provinces). We performed a high-resolution analysis of haplogroup H by control region sequencing and coding SNP screening of the 337 individuals harboring this maternal marker. Our results were compared with those of a wide panel of populations, including individuals from Iberia, the Maghreb, and other regions around the Mediterranean, collected from the literature.
RESULTS:
Both Andalusian subpopulations showed a typical western European profile for the internal composition of clade H, but eastern Andalusians from Granada also revealed interesting traces from the eastern Mediterranean. The basal nodes of the most frequent H sub-haplogroups, H1 and H3, harbored many individuals of Iberian and Maghrebian origins. Derived haplotypes were found in both regions; haplotypes were shared far more frequently between Andalusia and Morocco than between Andalusia and the rest of the Maghreb. These and previous results indicate intense, ancient and sustained contact among populations on both sides of the Mediterranean.
CONCLUSIONS:
Our genetic data on mtDNA diversity, combined with corresponding archaeological similarities, provide support for arguments favoring prehistoric bonds with a genetic legacy traceable in extant populations. Furthermore, the results presented here indicate that the Strait of Gibraltar and the adjacent Alboran Sea, which have often been assumed to be an insurmountable geographic barrier in prehistory, served as a FREQUENTLY traveled route between continents.

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Without data you are just another person with an opinion - Deming

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xyyman
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As I said many times. Europeans are depigmented Africans...BOTH male and females. The women arrived first and met the black Europeans....He! HE! Just kidding, but you get the point.
And before the fucgked questions start being asked. Autosomally these mtDNA H Africans carried "Eurasian" ancestry 21,000 years ago.


Quote:
" This technical progress increased phylogenetic resolution, thus demonstrating that i) the number of internal branches shaping clade H is significantly greater than in other mtDNA Hgs widespread in Europe [7], and ii) the observed Hg H variation in eastern regions (e.g., Near/ Middle East and Caucasus) shows MARKED DIFFERENCES to that found in western Europe [9]."

" The estimated coalescence time for Hg H (~21,000 years ago, ya) has led to the proposal that the clade was involved in a post-glacial population reexpansion from southwestern Europe to the rest of the continent."

The pre-historic distribution of mitochondrial DNA haplogroup H in Africa and Europe May2017

--------------------
Without data you are just another person with an opinion - Deming

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xyyman
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To those who don't get it. This is a rebuttal to Kefi et al. "The war is on!!!". Europeans are fighting back. Let us do a deep analysis. No stupid comments.

Keep in mind this is prior to 3000ya Pgani et al (when the supposed "Eurasian" back-migrated.)

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Without data you are just another person with an opinion - Deming

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xyyman
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I wasn't aware they completely sequenced "African" lineage in Spain...proving a pre-historic connection ...before slavery lol!. Now these fools are trying to spin that L, M U6 is African ....BUT!!!!!!! but H. A big ..but! SMH. Look at the data.

But this paper proves my point. There seems to have a been an ancient now submerged connection between West Africa and Europe. There is a heavy African presence not only on the western main land of Europe but definitely the Islands off both land masses. Sao Tome Prince', Cape Verde Canary Islands etc and...and now Western Iberia. Remember Eva Fernandez found more than 50% SSA lineage in ancient Iberia. Which no one speaks about.


Quote:" The complete sequencing of African mtDNA lineages found in the
Andalusian gene pool [19] have interestingly revealed the occurrence of ancient trans-continental contact
between northwestern Africa and Iberia
,"

QUOTE:
" the two territories exhibits significant genetic differentiation [18]. The population structuring seems to be primarily
caused by the differential weight of African lineages U6, M1 and L, which are far more represented in the
western than in eastern Andalusia. The complete sequencing of African mtDNA lineages found in the
Andalusian gene pool [19] have interestingly revealed the occurrence of ancient trans-continental contact
between northwestern Africa and Iberia
, with Andalusia being the Atlantic side of the Peninsula where most
African maternal traces are concentrated when compared to the rest of Europe."

--------------------
Without data you are just another person with an opinion - Deming

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the lioness,
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Europeans are more similar maternally to North Africans than all other Africans are to North Africans
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xyyman
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North Africans are a subset of Southern Africans and Europeans are a subset of North Africans. Don't you get that? There is a reason R1b-M269 is found in pre-colonial Island West Africans. There is a reason why Cape Verde Islanders show remnants of La Brana. This is not rocket science.

What is "more similar"? Based Upon STR Berbers are "Negros". Based Upon yDNA most North Africans/Berbers are ....African as much as modern SSA. So again, define "more similar"? Are you saying the Europeans women were concubines of Africans? You know I don't believe that BS like some of you. That is a contrive story to explain the high frequency of mtDNA H in Africa. It is BS. There were no European female slaves in North Africa. The presence of mtDNA H in Africa proceeds the presence of mtDNA in Europe. If you read this study, haplotypes of mtDNA H in Italy are DIFFERENT from mtDNA H in Iberia. Meaning?
Similarly you will find mtDNA H in Tunisia will be similar to mtDNA H in Italy. It is a continuum. European women are a subset of African women. When they get the guts and fortitude to do a deep dive on R1b-M269 between Europe and Africa they will make the same observation for the men. Sergi was correct. . This is not rocket science. There never was and never will be any migration from the Steppes of Asia as the racialist believes.

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the lioness,
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quote:
Originally posted by xyyman:
North Africans are a subset of Southern Africans and Europeans are a subset of North Africans. Don't you get that? There is a reason R1b-M269 is found in pre-colonial Island West Africans. There is a reason why Cape Verde Islanders show remnants of La Brana. This is not rocket science.

What is "more similar"? Based Upon STR Berbers are "Negros". Based Upon yDNA most North Africans/Berbers are ....African as much as modern SSA. So again, define "more similar"? Are you saying the Europeans women were concubines of Africans? You know I don't believe that BS like some of you. That is a contrive story to explain the high frequency of mtDNA H in Africa. It is BS. There were no European female slaves in North Africa. The presence of mtDNA H in Africa proceeds the presence of mtDNA in Europe. If you read this study, haplotypes of mtDNA H in Italy are DIFFERENT from mtDNA H in Iberia. Meaning?
Similarly you will find mtDNA H in Tunisia will be similar to mtDNA H in Italy. It is a continuum. European women are a subset of African women. When they get the guts and fortitude to do a deep dive on R1b-M269 between Europe and Africa they will make the same observation for the men. Sergi was correct. . This is not rocket science. There never was and never will be any migration from the Steppes of Asia as the racialist believes.

Again for whatever reason,
Europeans are more similar to North Africans maternally than other Africans are to North Africans

Africans who are not H carriers are more different maternally from Africans who are H carriers and Europeans

So the word "African" becomes of less importance in this context.

The genetics override the geographic terms.
Maternally we have the H carriers and we have the L/A/B carriers

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xyyman
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Quote: "for whatever reason" SMH

The reason is....European women lineage is a subset of African female lineage. "Pillars of Hercules" study. Africans carry the basal clade of mtDNA H and Africans carry haplotypes of H NOT found in European women but Africans carry ALL haplotypes found in European women. In other words European women are a subset of African women. There is not ambiguity about that FACT. They can spin frequency till the cows come hope. That will never change, Europeans are depigmented Africans. No doubt about that. Just as the AEians are indigenous Africans based upon the even the recent released paper. That is what the data shows even when they try to spin the frequency of haplogroups BS and selectively chose ONLY three haplogroups to disclose. The North African men are PN2 inclusive of siblings E1b1a and E1b1b . You can't get more African than that? Furthermore mtDNA H and E1b1b are around the same age and much older than E1b1a

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Without data you are just another person with an opinion - Deming

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the lioness,
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quote:
Originally posted by xyyman:
[QB] Quote: "for whatever reason" SMH

The reason is....European women lineage is a subset of African female lineage. "Pillars of Hercules" study. Africans carry the basal clade of mtDNA H and Africans carry haplotypes of H NOT found in European women but Africans carry ALL haplotypes found in European women. In other words European women are a subset of African women. There is not ambiguity about that FACT. They can spin frequency till the cows come hope.

People migrate so you can find tiny fractions of DNA all over the place
But by and large West Africans, South Africans and East Africans do not carry haplogroup H.

Haplogroup H in Africa is berber

So it makes more sense as per your theory, that the berbers are the forefathers of Europeans.

So when you say "Europeans are depigmented Africans" it has shock value but we all know that 95% of Africans are excluded.

Why not keep it real and say "Berbers are the forefathers of Europeans." if not
"North Africans are the forefathers of Europeans."

Obviously if you say "Africans" generally the first thing that comes to mind is the average African who does not look like these berber H carriers


 -
African Population density 2000

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xyyman
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you want shock value!? try, "AEians are less sub-saharan." Two can play that game.

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Ish Geber
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An important fact to factor in is:

quote:
Eastern and Saharan Africans shared the most alleles absent from other African populations examined (fig. S6D).

--Tishkoff et al.
"Genetic structure of Africans and African Americans"

quote:
"however, the time and the extent of genetic divergence between populations north and south of the Sahara remain poorly understood"
--Brenna Henn et al.

Published: January 12, 2012DOI: 10.1371/journal.pgen.1002397: 

"Genomic Ancestry of North Africans Supports Back-to-Africa Migrations"

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Forty2Tribes
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quote:
Originally posted by xyyman:
you want shock value!? try, "AEians are less sub-saharan." Two can play that game.

Exactly
The "Ancient Egyptian mummy genomes suggest an increase of Sub-Saharan African ancestry in post-Roman periods" media slogan is a push back against this 2015 mic drop
http://www.sciencedirect.com/sdfe/arp/media/1-s2.0-S0002929715001561-mmc1.pdf
 -

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the lioness,
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^ funnily he thinks xyyman is going to agree with this chart


quote:

we estimated the average proportion of non-African ancestry in the Egyptians to be 80% and dated the midpoint of the admixture event by using ALDER20 to around 750 years ago (Table S2), consistent with the Islamic expansion and dates reported previously

-- Tracing the Route of Modern Humans out of Africa by Using 225 Human Genome Sequences from Ethiopians and Egyptians
2015

Luca Pagani

(primarily J1 19.7% and J2, 12.2% see Luis et al 2004)
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Forty2Tribes
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quote:
Originally posted by the lioness,:
^ funnily he thinks xyyman is going to agree with this chart


quote:

we estimated the average proportion of non-African ancestry in the Egyptians to be 80% and dated the midpoint of the admixture event by using ALDER20 to around 750 years ago (Table S2), consistent with the Islamic expansion and dates reported previously

-- Tracing the Route of Modern Humans out of Africa by Using 225 Human Genome Sequences from Ethiopians and Egyptians
2015

Luca Pagani

(primarily J1 19.7% and J2, 12.2% see Luis et al 2004)
I don't expect him to. I think that number is flawed too. The point is what happens after
quote:
admixture event by using ALDER20 to around 750 years ago
is removed and where that narrative takes you.
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Elmaestro
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quote:
Originally posted by Fourty2Tribes:
http://www.sciencedirect.com/sdfe/arp/media/1-s2.0-S0002929715001561-mmc1.pdf
 - [/QB]

I wasn't really around when this study was a big thing, but there's a particular point I feel most people who posted this took for granted... or overlooked.

..Look at the Ethiopian populations before and after "Masking" (Wolayta, Gumuz, Somali, Amhara) and compare what happened to them with what happened to the Egyptians.

Notice that populations with the most "Eurasian" ancestry are closer to YRI after masking than the more "SSA" ones, for instance, Eyptians and Amhara, roughly 80% & 60% Eurasian respectively. Why are the more SSA populations without Eurasian Admixture more distant from the YRI, & not only that, why are they so distant from each other after masking?

that supervised chart actually blotched indigenous East African diversity, & components hidden due to reentry by nearby Eurasians.

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Tukuler
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Nearby Eurasians or nearby Afrasians?

Is there another Factor at play other than reentry?

OOA genomes were only an Arabian Plate/Levant bound bottleneck subset.

It wasn't a complete desertion of those particular genetic materials from the main continent.

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Ish Geber
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quote:
Originally posted by the lioness,:
^ funnily he thinks xyyman is going to agree with this chart


quote:

we estimated the average proportion of non-African ancestry in the Egyptians to be 80% and dated the midpoint of the admixture event by using ALDER20 to around 750 years ago (Table S2), consistent with the Islamic expansion and dates reported previously

-- Tracing the Route of Modern Humans out of Africa by Using 225 Human Genome Sequences from Ethiopians and Egyptians
2015

Luca Pagani

(primarily J1 19.7% and J2, 12.2% see Luis et al 2004)
LOL Pathetic.

quote:
To resume, our results clearly reject the scenario put forward so far of a strict correlation between the Arab expansion in historical times and the overall pattern of distribution of J1-related chromosomes. Similarly, the causal association between STR-defined haplotypes and ethnic groups appear without any robust support, making its use inadequate for forensic or genealogical purposes. Instead, J1 variation provided the genetic background to correlate climatic changes to human demographic and socio-cultural events scarcely documented in the archaeological record – the dispersal of hunter gatherers after the termination of glacial conditions in the late Pleistocene and the desertification-driven retreat of tribes of Saharan and Arabian foragers in the transition to a food-producing economy.
—Sergio Tofanelli et al.

J1-M267 Y lineage marks climate-driven pre-historical human displacements

European Journal of Human Genetics (2009) 17, 1520 – 1524

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Forty2Tribes
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quote:
Originally posted by Elmaestro:
I wasn't really around when this study was a big thing, but there's a particular point I feel most people who posted this took for granted... or overlooked.

..Look at the Ethiopian populations before and after "Masking" (Wolayta, Gumuz, Somali, Amhara) and compare what happened to them with what happened to the Egyptians.

Notice that populations with the most "Eurasian" ancestry are closer to YRI after masking than the more "SSA" ones, for instance, Eyptians and Amhara, roughly 80% & 60% Eurasian respectively. Why are the more SSA populations without Eurasian Admixture more distant from the YRI, & not only that, why are they so distant from each other after masking?

that supervised chart actually blotched indigenous East African diversity, & components hidden due to reentry by nearby Eurasians.

Good point
Isnt that systematic though? I'm still trying to figure out how these numbers are determined. It looks like percentage of haplogroups with Ls as African.

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Elmaestro
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--Originally posted by Tukuler:
--"Nearby Eurasians or nearby Afrasians?"

Eurasians or Afrasans already mixed with Eurasians.

--"Is there another Factor at play other than reentry?
--OOA genomes were only an Arabian Plate/Levant bound bottleneck subset.
--It wasn't a complete desertion of those particular genetic materials from the main continent. "


That's partially what I was getting at, like, imagine whatever remnants of East African Ancestry remaining in modern Eurasians being masked out to show how "Sub-Saharan African" the east African population are as of now?

Also prehistoric components shared by Europeans and east Africans but also shared with other Africans like YRI, are going to be dropped, Like if we revisit schlebusch 2017

 -

Most contemporary East African populations could have had ancestors that diverged @ 'East africa2' ..that clade is also a precursor to Europeans, possibly 2 fold, If you mask out CEU, who are a combination of HGS like LBK, AnatoliaNs, Eneolithics..etc, your probably gonna include some indigenous African components too for example.

@Fourty2Tribes

Not really systematic, just linear reasoning at best. how aware they were when organizing the study back then about the full spectrum of indigenous East African diversity have to be considered. In layman's terms, they took their CEU sample, and negated most components shared with the Africans in their dataset. basically Aficans - CUE = SSA w/o non African Admixture.

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Forty2Tribes
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What I mean by systematic is that this is in every genetic study and most calculations with east Africans and Africans in general.
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Tukuler
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Please leave my wordage intact.
Preferably within a quote box.
Thanks.


Lemme define my use of Afrasian.

It ain't Afrasan (Afrisian) -- linguistic.
Weren't no such phylum 120,000-55,000
years ago when OoA was going down.

Eur Asian = a super continent.

Afr Asian = that part of 'Asia' which
came from Africa (Levant + Arabian Plate).

Way I see it weren't no one way street out
of Africa. It's a two way street in my book.

From the first successful Hss going back and
forth, to historically modern Afrasians who're
infused with molecular genetics that never left
Africa because it never existed in Africa.

Mutations and combinations that sprang up in
Europe, west central east and south Asia, and
the Pacific, along with ingressions from Archaics
there, are the only non-African (thoroughly Eurasian) shit that shoulda got masked.

CEU and CHB needed get their own African masked
off first. Otherwise they can't be used to mask
bona fide Eurasian components in any peoples.


It's not a matter of if we're saying the same
thing or not. This is what I am saying. If I had
Davidski's resources I'd make a more accurate
Fst than the one referenced. And I damn sure
know that you Beyoku and Swenet could too!


Admixture happened in Afrasia and it wasn't no
backflow. The peoples from northwest north and
east of Afrasia who migrated there were not from
Africa so couldn't go back to Africa.

Only the Afrasians could back migrate.
Both before and after they took exotic
true Eurasian bedmates.


Me? Right now I'm tired of ENF related
shit and qpGraphs with their non-agreeing
yet valid multiple models all in the same
report. Sure, I'll have to come around to
them again in the future, with their limit
of only two solid line descent splits per clade.

BTW what are those numbers by the solid lines?

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I'm just another point of view. What's yours? Unpublished work © 2004 - 2023 YYT al~Takruri
Authentic Africana over race-serving ethnocentricisms, Afro, Euro, or whatever.

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Elmaestro
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"shoulda, shoulda, shoulda" ...it aint my study, I ain't responsible for this outcome.

for the point I was trying to make, it doesn't matter if you want to focus on ENF, EEF, LNF or BFFs, point of the matter is Europeans (CEU) have African admixture whether ancestral, divergent or recent. And East Africans have recent Eurasian Admixture from where ever d'fuq.

The pattern I pointed out for the Fst distances can be explained easiest by going to the root, "basal" populations or whatever. more recent African geneflow outside the continent might play a part, but I'll grab the low hanging fruit, for which I don't have to simultaneously explain which recent African migration OOA brings both west Africans and Europeans closer to East Africans... AND brings Ethiopians closer to each other.

yo, if you have any insight on which populations/movements might yield something similar, please share, I'm not the best historian on here.

The Numbers by the solid lines are drift lengths

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Tukuler
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O I C. all that matters is
what you want to focus on.


Your point is your point
My point is my point

They don't have to agree or
even dovetail in the least.
Norma's the one build off
the other.


We aren't even talking
about the same thing.

Of course you're going to
prefer you explanation and
think it's simplest but it
isn't afaic. But I don't
shoot it down.

I reject that Fst altogether.
I stated why and I couldn't
give a shit about all this
'Lazian' statistical yet
nonexistent populations.

Simplest? There was no traps sieves or barriers
stopping people going back and forth across the
Red Sea or the Sinai whenever they wanted to .

All that linear movement event nonsense of
Eurasian OOA and Eurasian back migration is
myopic afaic. I'm not going to sit up here
snd act like what I think about it is the only
way it could have been. Nor am I going to poo poo
Fresh ideas because they are alterned to mine. One
Is as good as the other as long as there's evidence
in support of the logic.

I couldn't give a shit about basal this basal that
or basal the other thing. Nor the Laz alphabet soup
everybody's drunk on. What the fuck happened to stones
bones industries economies diets diseases regional
dynamics and what not?


And thanks for teaching me what those numbers mean .I couldn't access the manual

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I'm just another point of view. What's yours? Unpublished work © 2004 - 2023 YYT al~Takruri
Authentic Africana over race-serving ethnocentricisms, Afro, Euro, or whatever.

Posts: 8179 | From: the Tekrur straddling Senegal & Mauritania | Registered: Dec 2011  |  IP: Logged | Report this post to a Moderator
   

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