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[QUOTE]Originally posted by MindoverMatter718: [QB] Furthermore, the derived allele and ancestral allele does seem to show a correlation with lighter and darker skinned populations, and it seems the frequency of the SLC24A5 111*A allele outside of Europe is largely accounted for by high frequencies in geographically proximate populations in northern Africa, the Middle East, and Pakistan (ranging from 62% to 100%). What does this tell you Chimu? Genetic Evidence for the Convergent Evolution of Light Skin in Europeans and East Asians Heather L. Norton,*1 Rick A. Kittles [QUOTE] In contrast, the [b]**ancestral allele**[/b] associated with [b]**dark pigmentation**[/b] has a shared high frequency in [b]**sub- Saharan African and Island Melanesians**.[/b]A notable exception is the relatively lightly pigmented San population of Southern Africa where the [b]**derived allele**[/b] predominates (93%), although this may be simply due to small sample size (n514). The distributions of the [b]**derived and ancestral alleles**[/b] at TYR A192C, MATP C374G, and SLC24A5 A111G are consistent with the FST results suggesting strong Europeans pecific divergence at these loci. The *derived allele* at TYR, 192*A (previously linked with lighter pigmentation [Shriver et al. 2003]), has a frequency of 38% among European populations but a frequency of only 14% among non-Europeans. The differences between Europeans and non-Europeans for the MATP 374*G and SLC24A5 111*A alleles (both derived alleles associated with lighter pigmentation) were even more striking (MATP European 5 87%; MATP non-European 5 17%; SLC24A5 European 5 100%; SLC24A5 non-European 5 46%). [b]The frequency of the SLC24A5 111*A allele outside of Europe is largely accounted for by high frequencies in geographically proximate populations in northern Africa, the Middle East, and Pakistan (ranging from 62% to 100%).[/b] [/QUOTE] [/QB][/QUOTE]
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