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[QUOTE]Originally posted by MindoverMatter718: [QB] :confused: So this derived allele was an imaginary one you're saying, made up fictitiously? Wouldn't that throw this whole study into question if there is no derived allele and instead it was made up, even though as shown it's specifically mentioned? Maybe Norton needs to read her study again, because she's clearly contradicting herself. In any event, you make no sense! Genetic Evidence for the Convergent Evolution of Light Skin in Europeans and East Asians Heather L. Norton,*1 Rick A. Kittles [QUOTE] In contrast, the [b]**ancestral allele**[/b] associated with [b]**dark pigmentation**[/b] has a shared high frequency in [b]**sub- Saharan African and Island Melanesians**.[/b]A notable exception is the relatively lightly pigmented San population of Southern Africa where the [b]**derived allele**[/b] predominates (93%), although this may be simply due to small sample size (n514). The distributions of the [b]**derived and ancestral alleles**[/b] at TYR A192C, MATP C374G, and SLC24A5 A111G are consistent with the FST results suggesting strong Europeans pecific divergence at these loci. The *derived allele* at TYR, 192*A (previously linked with lighter pigmentation [Shriver et al. 2003]), has a frequency of 38% among European populations but a frequency of only 14% among non-Europeans. The differences between Europeans and non-Europeans for the MATP 374*G and SLC24A5 111*A alleles (both derived alleles associated with lighter pigmentation) were even more striking (MATP European 5 87%; MATP non-European 5 17%; SLC24A5 European 5 100%; SLC24A5 non-European 5 46%). [b]The frequency of the SLC24A5 111*A allele outside of Europe is largely accounted for by high frequencies in geographically proximate populations in northern Africa, the Middle East, and Pakistan (ranging from 62% to 100%).[/b] [/QUOTE] [/QB][/QUOTE]
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