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Ghana And the dangerous skin-bleaching craze
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[QUOTE]Originally posted by meninarmer: [QB] [QUOTE]Originally posted by MindoverMatter718: [qb] ^Too bad for you not all Europeans look like that... [IMG]http://images.google.com/url?source=imgres&ct=tbn&q=http://img501.imageshack.us/img501/8266/vanilliaeischeid234gerth4.jpg&usg=AFQjCNH6tTKXYBEyOa4TqbdLwvhY_M_Q_A[/IMG] [IMG]http://images.google.com/url?source=imgres&ct=tbn&q=http://www.freewebs.com/romaniangirl/grad_alina.jpg&usg=AFQjCNGvgAZ6c24sQa_28LwbjXk7O1pZKg[/IMG] [/qb][/QUOTE]All forms of albinism result from the dysfunction of TYR and/or other melanogenic proteins, which leads to impaired pigmentation of the skin, hair and eyes (50). By its nature, only pigmented tissues are affected; to date, five types of albinism have been defined that map to five distinct pigment-related loci. [b]Mutations in any of those genes impact TYR activity either directly or indirectly[/b] : [b]oculocutaneous albinism (OCA) type 1 (TYR)[/b] and OCA3 (TYRP1) by leading to proteasomal degradation of TYR, OCA2 (P) and [b]OCA4 (MATP) by disrupting the sorting of functional TYR to melanosomes.[/b] OA1 (OA1) impairs melanosome biogenesis and [b]pigmentation by an as yet unknown mechanism and thereby disrupts the production of melanin[/b] (51). Yuji Yamaguchi{ddagger}§1, Michaela Brenner{ddagger}, and Vincent J. Hearing{ddagger}2 From the {ddagger}Laboratory of Cell Biology, NCI, National Institutes of Health, Bethesda, Maryland 20892 [/QB][/QUOTE]
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