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Salvia is not 'fun' in the way that alcohol or cannabis can be. If you try to party with salvia you probably will not have a good experience. Salvia is a consciousness-changing herb that can be used in a vision quest, or in a healing ritual. In the right setting, salvia makes it possible to see visions. It is an herb with a long tradition of sacred use. It is useful for deep meditation. It is best taken in a quiet, nearly dark room; either alone, or with one or two good friends present.
—Salvia divinorum User's Guide

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• Increased insight: 47%

• Improved mood: 44.8%

• Increased connection with Universe or Nature: 39.8%

• Increased self-confidence: 21.6%

• Improved concentration: 19.4%

Other commonly reported effects include:

* Feelings of calmness: 42.2%
* Weird thoughts: 36.4%
* Things seeming unreal: 32.4%
* Floating feelings: 32%
* Mind racing: 23.2%
* Feeling lightheaded: 22.2%

Long term
It has been suggested that the long-term effects of Salvia use may include déjà vu.[77] The Baggott survey found little evidence of addictive potential (chemical dependence) in its survey population. 0.6% percent of respondents reported feeling addicted to or dependent on salvia at some point, and 1.2% reported strong cravings. About this the researchers said "there were too few of these individuals to interpret their reports with any confidence".

Most users report no hangover or negative after-effects (e.g. withdrawal, comedown or rebound effect) the next day. This is consistent with the apparent low toxicity of Salvia indicated by research conducted at the University of Nebraska.[10]

I say go for it
 

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Professor Bryan L. Roth, director of the National Institute on Mental Health's Psychoactive Drug Screening Program, has said

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We think that drugs derived from the active ingredient could be useful for a range of diseases: Alzheimer's, depression, schizophrenia, chronic pain and even AIDS or HIV.
—Viren 2007-08-23 (US Media)

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Clinical pharmacologist John Mendelsohn has also said

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There may be some derivatives that could be made that would actually be active against cancer and HIV [...] At the present time, there are a lot of therapeutic targets that have many people excited.

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