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DNAtribes analysis on Tel Amarna mummies
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[QUOTE]Originally posted by Tukuler: [QB] popSTR is compatible w/MiniFiler. Let's use 3 major geographic population sets [list=a] [*]Africa (including Mzab) [*]Europe [*]South West Asia [/list] popSTR Db is nowhere near as robust as DNAtribes Db but will suit the purpose of example to show the MiniFiler 8 STR haplotypes can and do validly delineate geographies and ethnies Using the same algorithm as before we [list=1] [*]select a mummy [*]note its 8 loci's pair values [*]match them to popSTRs results [/list] Using Tut for example we find the pooled African set as perfect a match as our tool allows. And since the haplotypes match for all given alleles we don't need to check frequencies for the most likely match. If we want complete ranking for all three sets we'd have to take the highest frequencies of matching alleles into consideration noting where gaps are insignificant. But here we can see by simple matching that Europe is likelier than SW Asia though the latter has more of the highest frequencies for some loci's alleles. And no, the science is NOT that crude. [IMG]http://img210.imageshack.us/img210/5269/popstr02.gif[/IMG] As with our earlier comparison of DNAtribes' MLIs against popSTR's results we find the allele pairs of two loci to be decisive in a one to one match of Tut's mummy to a specific population. They are [list=1] [*]D21S11 = 29,34 [*]CSF1PO = 06,12 [/list] This should quell internet "yelps" that [URL=http://marketing.appliedbiosystems.com/mk/get/MINIFILER_LANDING?isource=fr_E_Alias_Minifiler_ProdRegMinifiler_20061114]Applied Biosystems' 8 loci AmpFℓSTR® MiniFiler™ PCR Amplification Kit (link)[/URL] cannot accurately distinguish an individual's major geographic population affinity just as the earlier check showed it can filter intra-continental regional probability. [/QB][/QUOTE]
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