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[QUOTE]Originally posted by huy60: [QB] And this too, is just for you. http://www.biomedcentral.com/1471-2156/10/59 The recent resolutions of the CDEF-M168 tripartite structure to the bipartite DE-YAP and CF-P143 [16, 31] extends the conversation regarding the early successful colonization of Eurasia. While several scenarios remain potentially possible the most parsimonious model is the most prudent. This model proposes the successful colonization of Eurasia by migration(s) of populations containing precursor Y-chromosome founder macrohaplogroup CDET-M168 and basal mtDNA L3 representatives. Regions near but external to northeast Africa, like the Levant or the southern Arabian Peninsula, could have served as an incubator for the early diversification of non-African uniparental haplogroup varieties like Y chromosome DE-YAP*, CF-P143* and mtDNA M and N molecular ancestors. These would have spread globally and diversified over time and space. [b]This model would imply that both CF-P143 and the DE-YAP evolved nearby but outside Africa. One DE-YAP* ancestor would have spread to Asia and evolved to haplogroup D while another DE-YAP* returned to northeast Africa and evolved into hg E.[/b] It is noteworthy that DE-YAP* has been detected at low frequency in Africa [37]. Again, this hypothesis has its mtDNA counterpart as it is well documented that, in the Palaeolithic, at least three clades (X1, U6, M1) derived respectively from the three main Eurasian macrohaplogroups (N, R, M) came back to North Africa from Asia [38-42]. edit: http://www.pnas.org/content/106/48/20174.full The similarity of patterns of different mutants indicates some secondary expansions. It is also interesting to sum the distributions of different haplogroups descending from the same mutation, as for example D and E, which both descend from DE-YAP, the first mutation that split into the E branch that perhaps returned to Africa (or arose there), whereas the other branch, D, is found today mainly in the Himalayas and Japan. [/QB][/QUOTE]
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