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[QUOTE]Originally posted by Narmerthoth: [QB] [QUOTE]Originally posted by Quetzalcoatl: [qb] [QUOTE]Originally posted by Narmerthoth: [qb] TIagree with this, however the sequence of variation order is significant in influence priority, Whereas random mutation followed by genetic drift, and lastly, environmental adaptation occur in that order. Why, because Yellow, red, white (pinkish) are transformations due to genetic mutation/genetic drift, and even social constructs (Asia as example) moreso than environmental adaptation.[/QUOTE][/qb] However, adaptation to the environment (written large) is the ultimate cause- selecting random mutations that allow more reproductive success and fixing of alleles. Right? [/qb][/QUOTE]I disagree. The human immune system is a closed loop adaptive system, meaning external stimulus triggers internal response. If the response mechanism is broken, then the system become partially or completely inoperable. In the case of UV, external body sensors detect UV levels and respond accordingly to protect the body. In the case of excess UV, increased melanin production is triggered. In the case of lower UV, a small percentage decrease is triggered. In the case of OCA dominate mutation where little to no Eumelanin production is possible, the feedback path is blocked. In this latter case, there is no actual UV response adoption, is there is no actual skin level positive selection. [IMG]http://i32.photobucket.com/albums/d25/GoldenMenes/melanosomestokeratinocyte.gif[/IMG] There are other environmental responses such as, longer/thicker hair, more body area covered by hair, additional sub-skin circulation system for heat removal, additional eye covering for photo-sensitivity, etc. These are responses to compensate for the original system being broken. However, after a thousand years of observing African Albinos where the mutation is dominate, we have yet to see any of the above selection traits manifested in any of them. [IMG]http://i32.photobucket.com/albums/d25/GoldenMenes/enhanced-buzz-21695-1274977194-0.jpg[/IMG] Black -> OCA -> Environment, define the distinct diversity of Humankind [IMG]http://i32.photobucket.com/albums/d25/GoldenMenes/skin-colors_1203_600x450.jpg[/IMG] [/QB][/QUOTE]
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