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[QUOTE]Originally posted by DD'eDeN: [QB] Ballito Beach boy Being able to extract DNA and then sequence the full genomes of ancient human remains from tropical coasts is often considered precarious because of the warm, humid climate. Yet, we have now demonstrated the successful sequencing of full genomes (i.e. gaining the information of all chromosomes – including autosomes, X-chromosomes, Y-chromosomes and mitochondrial DNA) obtained from Stone Age human remains found along the tropical east coast of southern Africa.1 With a minimalist sampling strategy, causing the least amount of morphological damage, we sequenced genome-wide data from three sets of approximately 2000-year-old human remains found 60 years ago on the Ballito and Doonside beaches of KwaZulu-Natal, South Africa. One set of remains – those of a young boy (Figure 1) – yielded a remarkably complete genome, where every position was covered by sequenced DNA (on average) 13 times Ancient human DNA: How sequencing the genome of a boy from Ballito Bay changed human history Marlize Lombard1 Mattias Jakobsson1,2,3 Carina Schlebusch1,2 AFFILIATIONS: 1Centre for Anthropological Research & Department of Anthropology and Development Studies, University of Johannesburg, Johannesburg, South Africa 2Department of Organismal Biology, Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden 3SciLife Lab, Uppsala, Sweden CORRESPONDENCE TO: Marlize Lombard EMAIL: mlombard@uj.ac.za KEYWORDS: human genome; hunter– gatherer; Homo sapiens; population split-time estimations HOW TO CITE: Lombard M, Jakobsson M, Schlebusch C. Ancient human DNA: How sequencing the genome of a boy from Ballito Bay changed human history. S Afr J Sci. 2018;114(1/2), Art. #a0253, 3 pages. http://dx.doi. org/10.17159/sajs.2018/a0253 [/QB][/QUOTE]
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