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DSC & Hawass(2010) Ancestry ...
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[QUOTE]Originally posted by Djehuti: [QB] [QUOTE]Originally posted by The Explorer: [qb] STRs simply allow a clade to be [i]phylogenetically[/i] placed within a particular [b]sub[/b]-clade, with the help of and secondary to, of course, [b]key binary[/b] markers. Yes, [i]guesswork[/i] of the probable clade is possible from a [i]whole set[/i] or at least a [i]considerable[/i] section of Y STR loci. However, it is a mistake to assume that STRs cannot mislead, since STR loci have been documented in various occasions to be [i]homoplasic[/i]. What is the significance of this; it can lead to wrong guesswork about a clade, without key binary marker information. They are also susceptible to reversions, since they are less stable than unique event polymorphisms. For an example, see: [URL=http://exploring-africa.blogspot.com/2008/05/examining-cases-for-or-against.html]Link[/URL] As for unique event polymorphisms; they are supposed to have occurred only one time in history, which is what makes them good markers of where and when a common ancestor emerged. Clusters or haplotypes (denoted by [i]characteristic[/i] STRs) help us track the migration path of a certain lineage, and associated possible time frames in which it occurred. [/qb][/QUOTE]Thanks very much, I understand now. [/QB][/QUOTE]
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