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1- Basic database of Nile Valley studies
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[QUOTE]Originally posted by zarahan- aka Enrique Cardova: [QB] "SLC24A5 was shown to play a pivotal role in skin pigmentation lightening in Europeans 10. Interestingly, the haplotype profile of SLC24A5 in CEU revealed a high affinity to aFM ( D aFM, MHG = 2) and a substantial distance to aHG ( D aHG, MHG = 28), as suggests that skin lightening associated with SLC24A5 originated from Near East, and likely was introduced into ancient Europeans via farming transition. This was strongly supported by a recent study based on 83 ancient DNA specimens 53." --Zhou et al 2015 (A Chronological Atlas of Natural Selection in the Human Genome during the Past Half-million Years. BioRxiv (quoted in Cochran). "We also found evidence of selection at two loci that affect skin pig mentation. The derived alleles 63 of rs1426654 at SLC24A5 and rs16891982 at SLC45A2 are, respectively, fixed and almost fixed in present -64 day Europeans 23,24. As previously reported 7,11,12, both derived alleles are absent or very rare in western 65 hunter -gatherers. suggesting that mainland European hunter -gatherers may have had dark skin 66 pigmentation. SLC45A2 first appears in our data at low frequency in the Early Neolithic, and increases 67 steadily in frequency until the present... In contrast, the derived allele of 69 SLC24A5 increases rapidly in frequency to around 0.9 in the Early Neolithic, suggesting that most of the 70 increase in frequency of this allele is due to its high frequency in the early farmers who migrated from the southeast at this time, although there is still strong evidence of ongoing selection after the arrival 72 of farming .." --Mathieson et al 2015. [/QB][/QUOTE]
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