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Ancient west Eurasian ancestry in southern and eastern Africa 2013
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[QUOTE]Originally posted by Swenet: [QB] What i find amusing is that some trolls just keep on lying their ass off. Science is clear on the matter; the derived SLC24A5 allele evinces positive selection in tropical populations due to its additional, non skin-color related functions it codes for, while other European skin pigmentation alleles that don't have these functions can easily experience purifying selection (get weeded out) in new environments where they're not advantageous (such as Southern Arabia, such as Ethiopia). Pagani et al already explained this, but, of course, it fell on deaf ears due to the charlatan's pre-existing commitment to his fairy tale and lying his ass off: [QUOTE]An intriguing consequence of admixture between populations is the opportunity for packages of genes to be “tested” in different environments. [b]As a result, the genomic regions containing functionally divergent genes might experience either positive or negative selection, depending on whether their adaptive contribution was beneficial or damaging in the new environment[/b], or whether it affected social factors such as sexual selection.[/QUOTE]--Pagani et al 2012 That some lying ass troll uses the lack of additional European skin color associated alleles, besides the SLC25A5 allele, as evidence that Ethiopian SLC25A5 is not a marker of Eurasian ancestry, is further evidence of the troll's inherent propensity to lie and distort. It's not uncommon for tropical populations with relatively high derived SLC24A5 to be low on other European skin pigmentation markers. Indeed, Sri Lankan populations display the same pattern: [QUOTE]The two genes SLC24A5 and SLC45A2 were recently identified as major determinants of pigmentation in humans and in other vertebrates. The allele p.A111T in the former gene and the allele p.L374F in the latter gene are both nearly fixed in light-skinned Europeans, and can therefore be considered ancestry informative marker (AIMs). AIMs are becoming useful for forensic identification of the phenotype from a DNA profile sampled, for example, from a crime scene. Here, we generate new allelic data for these two genes from samples of Chinese, Uygurs, Ghanaians, South African Xhosa, South African Europeans, and Sri Lankans (Tamils and Sinhalese). Our data confirm the earlier results and furthermore demonstrate that the [b]SLC45A2 allele is a more specific AIM than the SLC24A5 allele because the former clearly distinguishes the Sri Lankans from the Europeans.[/b][/QUOTE]--Soejima & Koda 2006 This is precisely what the lying troll doesn't mention in his ''objective'' posts, because it nukes his frivolous objection that such a scenario in Ethiopian populations contradicts Pagani et al. [/QB][/QUOTE]
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