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Ancient west Eurasian ancestry in southern and eastern Africa 2013
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[QUOTE]Originally posted by The Explorer: [QB] [QUOTE]Originally posted by Swenet: They are saying something that's even more damning to your troll case. Other than SLC24A5 they found no additional skin pigmentation genes in Ethiopians that co-occur and are protective in the high latitude environment they were originally, and still are, selected for. [/QUOTE]Now that it's been established that your "another" biological function for the SLC24A5 variant was a big fiasco of bullshit, let's deal with your next fiasco: Where, fuckhead queen, are we told specifically about that "[i]no additional skin pigmentation genes in Ethiopians that co-occur and are protective in the high latitude environment they were originally, and still are, selected for [/i]"? We know that they did not find skin pigmentation alleles that typically accompany the European distribution of SLC24A5, which was what you were just educated on but met with your thickheaded denials; you wouldn't happen to simply be repeating this very idea, in a supposedly "different" way--according to your stunted intellect, would you? [QUOTE] They then say the excess of SLC24A5 is due to its biological function.[/QUOTE]Ok? Tell us something that we don't already know from the paper, fuckhead queen. [QUOTE] If, [b]as you say[/b], [b]SLC24A5 got selected[/b] for in an [b]equatorial[/b] population because of their skin colour related function (lol!)[/QUOTE]Where do I say such a thing, moron? And I mean, a quote, not your usual paraphrasing psycho-babble. Manufacturing claims will not make you win an argument, my dumb servant. It does the opposite. [QUOTE] explain why complementary genes that have this function, which the Levant affinity having haplotypes say should have been present, aren't there. Start explaining, troll!![/QUOTE]I don't have to explain crap for your idiotic tales; that's your job--it came outta your ass. However, I will clue you on the no-brainer fact that Ethiopians have their own skin pigmentation genes like any other population. Otherwise, they would not have any pigmentation, you big fat moron! LOL PS: Clowns who look to you as some sort of a genetic "expert" on ES [of course, where else would such a dumb undertaking take place], and they know who they are, actually insult themselves by doing so. [QUOTE] [QUOTE]Originally posted by The Explorer: In other words, you fat dumb ass [b]has no ounce of evidence for that crazy ass speculation about some fictitious "weeding out" event[/b] that some how magically spoofed out other pigmentation genes from Europe[/QUOTE]Lying ass troll, the whole purpose of that segment of their paper was to test which of the genes that typically occur as ''packages'', have survived in Ethiopia's tropical environment, and which got weeded out: [QUOTE] An intriguing consequence of admixture between populations is the opportunity for packages of genes to be ‘‘tested’’ in different environments. As a result, the genomic regions containing functionally divergent genes [b]might experience[/b] either positive or [b]negative selection[/b], depending on whether their adaptive contribution was beneficial or [b]damaging in the new environment[/b], or whether it affected social factors such as sexual selection. [/QUOTE]--Pagani et al 2012[/QUOTE]You merely cited a piece that essentially repeats what I told your uneducated monkey ass about the inheriting of genes under selection as is (genes serving as "gene flow" indicators), and comes down to a matter of whether said selection is deleterious or advantageous, douchebag. The piece you are citing says absolutely nothing about "weeding out"; those are your dumb words, not the authors. Nor did they even say a damn thing about genes that "[i]typically occur as packages[/i]" or "[i]to test which of the genes that typically occur as ''packages'', have survived in Ethiopia's tropical environment[/i]"; again, those are your words. You are an illiterate dickhead par excellence, LOL. Rather, the authors "looked" for "such outlier regions of admixture"...and by "such", they are referring to regions under examination, whose divergence patterns may speak to a possible "biological function" of the sequence in question, be it potentially positive or negative. This is how the SlC24A5 allele stood out to the authors, hence leading them to do this, in their own words, as cited in my first post in this thread: [i][b]Given that SLC24A5 is one of the most highly differentiated genes between African and European[/b] populations, we then [b]looked for other highly differentiated genes[/b] among the outlier windows, [b]but found none[/b][/i] And [i]To [b]further investigate the effect of admixture[/b] on the [b]**genetic landscape of skin pigmentation** in Ethiopia[/b], we also [b]looked at other genes associated with pigmentation in Europe[/b]; however, [b]none were found in our outlier regions[/b].[/i] [QUOTE] To protect your previous lies, you're now lying like the pathologically lying dog that you are. Talk about being knee deep in your own excretions.[/QUOTE]There is only one liar--and a rather dumb one at that--in our exchange, and it is not me, I can assure you that. [QUOTE]Sure. Let me guess, UFOs exist and you've just had telepathic contact with Sasquatch. Lying ass troll, the Sri Lankan samples had an excess of SLC24A5, and a severe deficit of SLC45A2. Explain this under your crackpot theory that a severe minority of SLC24A5 correlated genes testify to an indigenous origin of SLC24A5. LMAO! [/QUOTE]You are the one who claimed to be reading my mind, and now you are accusing me of telepathy. You are one screwed up sick puppy. It therefore follows that you should know more about imaginary worlds of UFOs and extraterrestrials than I do. Secondly, you are asking me to explain an [b]irrelevant[/b] citation that you broached, but too dumb to understand on your own. The Sri Lankan case is neither a substitute nor analogous to the Ethiopian case, douchebag. The only remotely relevant thing your Sri Lankan case can possibly have on our exchange, is one that is advantageous to me, and detrimental to your dumb monkey ass. The SLC24A5 marker served as a weaker marker in differentiating the Sri Lankan and Europeans, in contrast to the SLC45A2. That's what that citation was speaking to. Don't fault me because you were blessed with brainlessness and not being able to read your own citations. :) [/QB][/QUOTE]
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