...
Post A Reply
my profile
|
directory
login
|
register
|
search
|
faq
|
forum home
»
EgyptSearch Forums
»
Egyptology
»
Ancient west Eurasian ancestry in southern and eastern Africa 2013
» Post A Reply
Post A Reply
Login Name:
Password:
Message Icon:
Message:
HTML is not enabled.
UBB Code™ is enabled.
[QUOTE]Originally posted by The Explorer: [QB] [QUOTE]Originally posted by Swenet: Trolling again. That your dumbass didn’t specifically mention ‘’tropical’’ doesn’t mean that I can’t hold it against you [/QUOTE]A plain text stumped your monkey ass, and you think some one else is dumb, LOL. A stupid donkey can out-read you. And no, imaginary things can't be held against real world things. [QUOTE]Trolling again. The paper doesn't say that the authors identify ''skin pigmentation as the likely phenotypic candidate of this selection''. It's your interpretation of what they're saying[/QUOTE]And the right interpretation, in contrast to your numbskull fairy tale. Get your care-taker, there is some reading to do: [i]"[b]Of the fourteen 40-SNP[/b] windows [b]observed with a Z-score > 2[/b], we [b]noted one that contained SLC24A5[/b] (MIM 113750). This gene is a major [b]contributor[/b] to the [b]pigmentation[/b] differences between Africans and Europeans and a strong candidate for positive selection in Europe.4"[/i] [i]"To further investigate the effect of admixture on the [b]**genetic landscape of skin pigmentation**[/b] in Ethiopia, we also looked at [b]other genes associated with pigmentation[/b] in Europe; however, [b]none were found in our outlier regions[/b]."[/i] [i]"[b]SLC24A5[/b] was within the top 5% of selection signals, whereas the gene was not detected as an outlier in the other groups of Ethiopians. The unusual history of this gene was further supported by the presence of the derived A allele of the SNP rs1834640, [b]associated[/b] with the light [b]skin pigmentation[/b] of Europeans and western Asians..."[/i] [i]"This putative migration from the Levant to Ethiopia, which is also supported by linguistic evidence, may have carried the derived western Eurasian [b]allele of SLC24A5[/b], which is [b]associated with[/b] light [b]skin pigmentation[/b]."[/i] The paper identifies skin pigmentation as phenotypic trait of the allele, not once but several times over. This has not deterred your thick monkey skull from saying that it's just my interpretation, just so your fairy tale unspecified "biological function" can have a companion. You are such a blank-headed fuckhead whore. [QUOTE]Hey, it’s not my fault you’re bewildered about the fact that they tested for SLC45A2 and came up short. That you don’t know this is further evidence that you’re way out of your league here.[/QUOTE]The section cited mentions nothing about SLC45A2 that you are apparently confusing with SLC24A5 (aka the subject of that section in the real world). You have gone bananas. Get it? stupid monkey...gone bananas, LOL. [QUOTE]LMAO. **Where** did they ''apply Z-scores’’ when they attempted to track down the other skin pigmentation genes? [/QUOTE]You confuse "look for" with "Z-scores", just because they happened to be mentioned in the same sentence. Of course, this is you staying true to form, as you confused other vastly different concepts on so many occasions. Here's the point: Z-scores were not applied to either "[i]investigate admixture[/i]" or "[i]to test which of the genes that typically occur as ''packages'', have survived in Ethiopia's tropical environment[/i]"; those moronic ideas come from your dumb monkey ass. The scoring was used to isolate regions that may be suggestive of either a positive [and thereof, a "biological function"] or negative selection. If one were just working with "[i]genes that typically occur as a package[/i]" just to see "[i]which survived in Ethiopia's tropical environment[/i]", then one simply needed to go straight to the location (which should already be known) of that "package", [i]of which SLC24A5 is supposedly "a part"[/i] (your words), and [b]look at[/b] the content. One would not need to "look for" the "package", my dumb servant. [QUOTE] Only a brainless troll such as yourself would use it against another poster that the authors state that they consulted the literature.[/QUOTE]I'd have to take it that a brainless troll is vastly smarter than a brainless fairy-tale telling monkey (you). Where do you see, ’’[i][b]looked at’’ the literature first[/b] to [b]identify which genes[/b] they [b]should be looking ‘’for’’[/b][/i]" in this: [i]To [b]further[/b] investigate the [b]effect of admixture[/b] on the [b]**genetic landscape of skin pigmentation**[/b] in Ethiopia, we also [b]looked at[/b] other [b]genes associated with pigmentation[/b] in Europe; however, [b]none were found in our outlier regions[/b].[/i] [QUOTE] [QUOTE]Originally posted by The Explorer: dumbass chump, they have different bio-histories[/QUOTE]Your spacey attempt to wilfully wish these facts away with some random mumbo jumbo blank no-brainer invocation of ’’differing bio-histories’’ [/QUOTE]You needed to be fed like a helpless baby with this "no-brainer", because apparently, you are not equipped with a brain to figure out on your own, that the differences stem from their different bio-histories; else you would not have asked that fuckheaded question. [QUOTE] [QUOTE]Originally posted by The Explorer: the authors had already decided upon which sequences to treat "African" and "non-African", henceforth why the study was fucked up.[/QUOTE]Ah, let me guess[/QUOTE]That's just what you do: guessing. If you used as much effort at actually reading and learning as you do at being incredibly stupid when not guessing imaginary things, then you'd get somewhere--not mindless drivels in circles. :) [/QB][/QUOTE]
Instant Graemlins
Instant UBB Code™
What is UBB Code™?
Options
Disable Graemlins in this post.
*** Click here to review this topic. ***
Contact Us
|
EgyptSearch!
(c) 2015 EgyptSearch.com
Powered by UBB.classic™ 6.7.3