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Ancient west Eurasian ancestry in southern and eastern Africa 2013
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[QUOTE]Originally posted by The Explorer: [QB] [QUOTE]Originally posted by The Explorer: which brings us to the question of why then, there seems to be indication (as shown in the Z-scores) that a derived variant is "selected for" in Ethiopians. [/QUOTE]I'd like to add another thing about these Z-scores, with regards to technicalities. Given the cut-off points picked by Pagani et al., there is no telling of whether say, any skin pigmentation alleles outside of SLC24A5, which may resemble variants of Europeans or "southwest Asians", could have had neutral-seeming occurrences across the tropical African populations analyzed; the only thing is, such occurrences will neither point to a drifting out (of deleterious alleles) event nor a natural selection event (for biologically or socially advantageous alleles), if that makes any sense or is even possible. Pagani et al.'s readers are only informed about the regions they deemed outliers, of which said alleles (outside of SLC24A5) would not have been a part. In any event, the prospect seems very unlikely given that Pagani et al. did not capitalize on it in any capacity, to bolster their "gene flow" theories. And in such a hypothetical scenario, even if they did, they'd run into a problem similar to the one outlined in my blog notes, with regards to the prospects of negative drift or natural selection. [/QB][/QUOTE]
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