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[QUOTE]Originally posted by beyoku: [QB] I don't think this program is saying you can pull STRs from SNP data. If this was possible there would be no need for separate STR and SNP companies. Particularly when dealing with the Y-Chromosome. Think of it as you trying to query specific letters (SNP) and numbers (STR) from a 10 paragraph output of text relating to the analysis of some object (Blood). The issue is the tool you used to generate those 10 paragraphs ONLY produces differing sequences of alphabetical letters. Therefore there are no Numbers in the text to query. You would then use a SECONDARY program to produce and query any numerical data. In DNA some folks only want the letters, other folks only want the numbers. Some need both. The numbers change faster than the letters so they can tell you more information about recent events. What is clear is when you run that program and it's says it's going to "test 100,000 to 500,000 SNPs". That is ALL ITS GOINT TO DO: Get you the values for those specific number of SNPs and NOTHING more. Or those specific STRs. Also think of it as a sex working going to the clinic to get tested for HIV. The test is ONLY look for the HIV virus (or however it works) its not going to tell her if she has Sisyphus, or Herpes or anything else, its only designed to look for that specific things and it she wants more she will have to take additional tests to look for those other specific diseases. :) Under a Y-Chromosome perspective there could be recent events that makes an STR profile look like a certain haplogroup be it the Atlantic modal halotype of European R1b, the Bantu modal STR pattern of E1b1a8 or the Cohen modal Haplotype of Jews. In the case of Jews and the CMH, it is highly split between 2 lineages, both J1 AND J2. Its is over 80% of their CHM when you test 6-12 STRs. What about the rest? Well that STR haployype is split between the various other haplogroups including E/G/H/Q/R. E/G/H/Q/R. Are SNPs, CHM is a 6 value STR profile. It exists within all the haplogroups listed above but mostly in J1/J2. If you test positive for CHM you would need a SNP test to know if you are Hap J or something else. Alternatively, If you test positive for J1/j2 you would need an STR test to know if you are positive for CHM because when you tested for J you ONLY tested for the presence of M172 and M267. NOTHING MORE. You dont know if you are Cohen Modal or the Arab Model. [/QB][/QUOTE]
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