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[QUOTE]Originally posted by beyoku: [QB] Here is the thing though - [URL=https://biology.stackexchange.com/questions/13608/what-is-the-difference-between-snp-and-str]As I know it, SNP data is not testing repeats. Its doesn't retrieve that information.[/URL] For Example if I go into my raw data. RIGHT NOW.....this is the exact data extracted by the Illumina sequencer Chip (Version 2 at 23andme). Back then it was 300-400k SNP's. Right now 23andme probably gives you 1 Million or more. Lets take a look 5 random SNP's from my Chromosome 5: Genes/Marker (SNP)/Genomic Position/Variants/Your Genotype 1 - intergenic rs10036054 2352730 C or T C / C 2 - intergenic rs10039326 2513346 A or G A / G 3 - intergenic rs1002647 2560537 A or G A / A 4 - intergenic rs10038374 2823353 A or G A / G 5 - ADAMTS16 rs10037656 5183783 A or G A / A You dont get the repeats. Looking at SNP number 2 I get the name of the SNP "rs10039326" and my Genotype "A/G". And you basically get this Hundreds of Thousands of times all at SPECIFIC SNP's that are known to be somewhat different when looking at world wide populations. If you could use a program to get STR information from SNP's then companies would not need you to sumbit new cheek swabs. You could just send your 23andme Raw data over to DNA Tribes. NO instead, if you want tribes STR analysis (or ANY STR analysis) you have to swab the cheek. If you send them your 23andme Raw data they can ONLY do a SNP analysis of that data....SNP imput = SNP output. Y-dna and Autosmal dna DO matter because If you are looking for autosomal SNPs you will not test for SNP's on the Y-chromosome because the Y nor the mtDNA contain Autosomal data. IN THE FUTURE...yeah if there was a test that just sequenced "every damn thing" you could potentially have all the data but there are issues with this: 1 - TIME - You are going to need a super computer to crunch all that data, [URL=https://www.youtube.com/watch?v=GrzWcLMBnco]I hope you got a snickers cause you aint going anywhere.[/URL] 2 - COSTS - It will not be cheap, it will not be 100. 3 - SIZE - You are going to end up with a Exabyte of data. 4 - We Dont even really know how large the genome IS. Nearly ever year there are resolving and "discovering" new SNP's, particularly on the Y-chromosome. IN actuality they are not "discovering" anything because those SNP's were already there, the number of positions in the human genome could reach into the quadrillions or something. Now if you can give an alternative example using evidence that shows you can get STRs from SNPs (when we already know you cannot get SNPs from STRs) The floor is yours. [/QB][/QUOTE]
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