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What's the difference between genome-wide data and mitochondrial genomes?
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[QUOTE]Originally posted by xyyman: [QB] Can someone post that plot showing Berbers are negros based on CODIS STRs? ------ Quote: "5 SNP versus STR In conclusion, the above numerical results of the comparative efficiency analysis of SNP and STR loci suggest that, without population data on SNP loci, a definite prescription regarding the required number of SNP loci cannot be given; to equal the power of the 13 STR loci with regard to genotypic match probability and/or paternity exclusion, however, somewhere in the range of 30±60 SNP loci would be needed, and they must be selected in such a manner that the assumption of independence across loci are met. Note that since SNP loci are biallelic (and hence, less mutable than the STR loci), the population substructure effect on SNP loci can be more severe than at the STR loci [37, 38]. Hence, more careful validation studies of SNP loci would be needed before implementing them for forensic and paternity analysis. In addition, the efficiency of SNP loci for interpreting DNA mixture evidence is far more reduced, necessitating a far (on STRs) Above and beyond this, the population data collected in this context can address many of the broad questions of the human genome diversity studies, such as the evolutionary relationship of populations, the implications of reduced genetic variation in specific populations, as well as inference of the past demographic history of populations [39]. The availability of commercial kits for genotyping the STR loci [6, 7] offers the opportunity to conduct population genetic analysis by pooling data through interlaboratory comparisons of results. Worldwide allele frequency data at these 13 STR loci also raises some questions that could yield information as to the mechanism of maintenance of genetic variation at these tetranucleotide loci." [/QB][/QUOTE]
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