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What's the difference between genome-wide data and mitochondrial genomes?
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[QUOTE]Originally posted by xyyman: [QB] So Capra is correct and Beyoku's gave an example why Uniparental markers (mtDNA or YDNA) can also be misleading when looking at MODERN or EXTANT samples. In ancient times/ samples there was very little intercontinental travel therefore uniparental markers and their haplotypes or sub-clades are very informative. SNPs are useless without TreeMix which show migration edges or events. That is why ALL objective TreeMix studies show a 2nd migration event from SSA to Europe with Sardinians and Iberians being the closest. This trend is displayed also in STR analysis and NOT SNP analysis. This is why SNP analysis as a standalone is useless and misleading. To Beyoku's point autosomal SNPs sometimes do NOT corroborate uniparental markers in "recent" admixed peoples like Obama and his offsprings. That may even apply to samples WITHIN Africa or even Europe. That is why aDNA is so important to understand migration history. There were no airplanes back then. Although some of us believe UFO/aliens built the pyramid and Africans could not have possible built it. lol! [QUOTE]Originally posted by capra: [Q] They're quite different things, you can't really put a percentage on it. A mitochondrial chromosome is actually a kidnapped bacterial chromosome; it's structure is completely different and it is much much smaller than a nuclear chromosome. It has a small set of very important genes and very little 'junk', while your nuclear genome has a buttload of genes, some not all that important, and loads of 'junk DNA'. mtDNA tells about one line of ancestry, so what percentage of your ancestors that is depends on how many generations back you go. If you go far enough back you could have no autosomal material whatsoever from your mitochondrial DNA ancestor, and they'd be one out of thousands. Y DNA is a nuclear chromosome but similarly traces one line of ancestry. Thing is, they are very good at tracing that particular line of descent. Autosomal DNA represents all your ancestry (on average anyway), but it's scrambled together and much harder to make a neat tree of relationships with it like you can with uniparental markers. In short there isn't any straightforward percentage you can put on it, just autosomal is much more informative overall if you can get it. [/QB][/QUOTE] [/QB][/QUOTE]
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