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[QUOTE]Originally posted by the lioness,: [QB] [QUOTE]Originally posted by Elmaestro: I haven't seen an autosomal study on the first Settlers of the Island, how do you know they were Berber? [/QB][/QUOTE]what about the thread topic article? Could it be there? [QUOTE] Population Genomic Analysis of Autosomal DNA A principal component analysis (PCA) of the five samples with the highest autosomal genome coverage, performed using genome-wide autosomal SNPs overlapping with Human Origins (HO) data [19 ; 20], reveals close affinity to modern Northwest African populations such as Tunisians and Algerians, but with a tendency (especially for individuals from Gran Canaria) to occupy a space outside modern Northwest African variation, closer to Europeans (Figures 2 and S2). However, outgroup f3 statistics [ 19] suggest that the Guanches share more genetic drift with non-African test populations than with African test populations, including Northwest African populations of Berber origin (Data S1, sheet 2). This observation is inconsistent with the PCA and the uniparental genetic marker data, indicating that the outgroup f3 statistic may be misleading, possibly due to the complex history of recent sub-Saharan admixture events in North African populations [ 12 ; 21] and the sensitivity of the f3 estimator to such patterns. This issue seems to extend to other statistics based on allele frequency correlations such as the D statistic [ 19] since D(Outgroup, Guanches; North African, Sardinian/Anatolian farmer) consistently produces highly significant positive values of D (Z > 4), which would imply a closer relationship between Guanches and Sardinians and Anatolian farmers than between Guanches and North African populations ( Data S1, sheet 3). The Guanches’ Berber-like affinity is further supported by ADMIXTURE [29] analysis (Figures 3 and S3), where Guanches largely behave like modern Berbers across all values of K. At K = 10, a Northwest African-specific ancestry component makes up the greatest amount of autosomal ancestry in the Guanche and Berber populations in the HO dataset, such as the Mozabite and Saharawi. It is also ubiquitous across other Northwest African populations with Berber ancestry, such as Algerians and Tunisians, consistent with the PCA results. This ancestry component is also represented in present-day Canary Islanders and at a low proportion in some South European populations (Figures 3 and S3). Interestingly, it is also shared by Middle Eastern populations, including some Natufians (Figure 3). Y chromosome E1b1b haplotypes (though not M183 variants) were also common in Natufians (circa 11,000 BCE) and pre-pottery Neolithic male individuals from the Levant (circa 7,000 BCE), suggesting some affinity to North Africans [30]. we show that the European conquest led to a decline in the overall degree of Guanche autosomal ancestry and provide an estimate that modern Canary Islanders (as represented by two individuals on the HO panel) carry between 16% and 31% autosomal ancestry derived from the Guanches (Table S3). --Genomic Analyses of Pre-European Conquest Human Remains from the Canary Islands Reveal Close Affinity to Modern North Africans [/QUOTE] [/QB][/QUOTE]
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