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How can SSA ancestry=True Negro and Niger Kongo, when....
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[QUOTE]Originally posted by xyyman: [QB] The “Luhya in Webuye, Kenya” (LWK) population has the most accentuated number of these rare variants!!!!!! Meaning an East Africans origin of Bantu. It may not be necessarily LWK but definitely East African =============== Quote: “ [b]H3Africa is driven by African investigators,[/b] and is anticipated to close the gaps of ‘missing’ heritability by increasing the number of causal variants identified within genes, from a dataset of over 70,000 individuals collected using standardized protocols 8,10. This catalogue of over 88 million high-quality variants from 26 populations has enhanced power to screen for common and rare variants that depict geographic and demographic differentiation2. This represents 80% (approximately 80 million) of all variants contributed or validated in the public dbSNP catalogue, with recent major enhancements for genetic variation [b]within several South Asian and African populations (24% and 28% of novel variants respectively)2.[/b] Most of the low-frequency (< 0.5%) variants likely to be of[b] functional significance are disproportionately present in individuals with substantial African ancestry,[/b] indicating bottlenecks in non-African populations2,3. The[b] “Luhya in Webuye, Kenya” (LWK) population has the most accentuated number of these rare variants. [/b]Paucity of data from African populations has restricted understanding of the heritable human genome variation.” [/QB][/QUOTE]
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