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Genetic evidence for the convergent evolution of light skin in Europeans
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[QUOTE]Originally posted by MindoverMatter718: [QB] [QUOTE]Originally posted by Mike111: [qb] [b]The mindless ones Mindless comments. [/b] Oh so now they're Asian albinos, no longer African albinos etc... huh? And the ancestral state mixed with the derived state and produced the derived state? [Confused] [b] African albinos were NOT a part of the study, therefore no samples were taken from African albinos.[/b][/qb][/QUOTE]Well here's the thing lil Mikey, if Europeans were descended from African albinos carrying this derived state, then we should see it amongst island Melanesians, who represent one of the oldest populations genetically living outside of Africa. But guess what lil Mikey? The Melanesians predominately carry the ancestral allele. So much for albinos walking OOA. [QUOTE]Originally posted by Mike111: [qb] So where did the derived state come from to begin with? The sky? No, it came from the ancestral state you dimwit. [b] Please see the definition of a Child's DNA (It is "derived") Therefore DIFFERENT from BOTH Parents.[/b][/qb][/QUOTE]No, lil Mikey, we're not talking about a childs DNA, we're talking about a few specific alleles, which do not even account for half of the DNA carried by one parent let alone both parents Jeez you're slow. [QUOTE]Originally posted by Mike111: [qb] Lol you're so fricken dumb it's kind of sad. I'll explain this one more time, the ancestral state is what humans carried when they walked out of Africa and populated the world, eventually going into Europe, it then mutated from its ancestral state in Europe into its derived state. [b] Derived is NOT the same as MUTATED.[/b][/qb][/QUOTE]Actually in this case it is, since the ancestral allele which predominates in Africa and island Melanesia is the same exact one that was analyzed in the study, wherein it showed to be mutated in this loci specifically in Europeans, this makes it the derived state, since we know humans walked OOA with the ancestral, not the derived. [QUOTE]Originally posted by Mike111: [qb] These alleles mutating outside of Africa and specifically in Europe debunks your case that Europeans descend from African albinos as showed the original ancestral state of the allele predominates in sub Saharan Africa and island Melanesia. [b] EXACTLY! The Africans did NOT change, their Children Did![/b][/qb][/QUOTE]Yes Mike, African children did change outside of Africa, which meant their children were African, hence Africans did change. Europeans didn't just drop out of the sky, they descend from Africans just like all other non Africas. Btw, thanks for noting that the descendants changed outside of Africa, now you're catching on. [QUOTE]Originally posted by Mike111: [qb] If the derived state represented albinos walking OOA then we should see these derived states in island Melanesian's etc.. but we don't, which means that it occurred after humans left Africa. [b] Nice try; but nobody said that Albinos represented the DERIVED state; They represent the MUTATED state. Their Children with Black Africans i.e. "White Europeans" represent the "DERIVED" state.[/b][/qb][/QUOTE]The derived state found specifically in Europeans is mutated from the original ancestral allele which in turn is found in Africa, hence its in a derived state when found in Europeans. You say African albinos represent Europeans and they walked out of Africa taking the same route all early humans did, hence we should see these derived/mutated alleles in island melanesians, but we don't lil Mikey. Again, so much for albinos walking OOA. [QUOTE]Originally posted by Mike111: [qb] So much for Europeans descending from African albinos. [b] Yes, there are almost 700 million of them.[/b][/qb][/QUOTE]Yea, and guess what? Fewer than 5 out of every 100,000 people in Europe are albinos. So much for "your theory" that Europeans are albinos. [i] http://medical-dictionary.thefreedictionary.com/Albino+people "Albinism is a rare disorder found in fewer than five people per 100,000 in the United States and Europe. Other parts of the world have a much higher rate; for example, albinism is found in about 20 out of every 100,000 people in southern Nigeria."[/i] [QUOTE]Originally posted by Mike111: [qb] P.S. just for kick, the San carry a derived state of the OCA2 allele which accounts somewhat for their lighterskin, you know OCA2 is supposed to the albino marker according to MK, so why aren't the San albinos? [b] Good question[/b][/qb][/QUOTE]Yes it is, but too bad for you that the San are not albinos and that the OCA2 gene plays a role in darker and lighter pigmentation worldwide. [i]Polymorphisms in 2 genes, [b]ASIP and OCA2, may play a shared role in shaping light and dark pigmentation across the globe[/b] , whereas SLC24A5, MATP, and TYR have a predominant role in the evolution of light skin in Europeans but not in East Asians. These findings support a case for the recent convergent evolution of a lighter pigmentation phenotype in Europeans and East Asians.[/i] [QUOTE]Originally posted by Mike111: [qb] Anyway, so now black men mix with albinos and make brown babies? Where else have you seen this? You make some of the dumbest statements, why? Because you make them up yourself. A black man with an albino woman, would either produce a baby with a full dark skin complexion as the dad, or if the fathers an OCA2 carrier another albino. No brown babies being created, that only happens when normally functioning people black and white produce a child, note Barack Obama. If his mother was an albino, then he should've came out his fathers complexion or as an albino, not inbetween. You jackass. LOL Whoa, wait a minute, on the one hand you say that the Sans light skin and derived OCA2 should make them Albino derived, then on the other hand you say that it is NOT possible??? Make up your mind![/qb][/QUOTE]No, you dipshit, I noted that since mutations in the OCA2 gene are associated with albinism, and the San carry a derived version of this gene, shouldn't that make them albinos according to you and MK? But their not albinos lil Mikey, you know why? Because the OCA2 gene accounts for lighter and darker skin pigmentation across the globe. Also guess what lil Mikey, the alleles specifically assocaiited with lighterskin in Europeans and no one else which are *derived alleles* at TYR, 192*A, MATP 374*G and SLC24A5 111*A alleles, are not the OCA2 gene. So much for Europeans being descended from African albinos. [QUOTE]Originally posted by Mike111: [qb] On second though, why not ponder this picture of a Black Father, Albino Mother, and two children of in-between color, one Albino, the other not.[/b] [IMG]http://www.ecmafrica.org/files/Albinos/Web%20albino%2015.jpg[/IMG] [/qb][/QUOTE]Where's the African albino mother? [/QB][/QUOTE]
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