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Genomic Ancestry of North Africans Supports Back-to-Africa Migrations Brenna M. Henn
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[QUOTE]Originally posted by Ponsford: [QB] "SubSaharan Africans has been identified as the part of the world with the greatest genetic diversity.This high levl of diversity causes difficulties for genome-wide association studies[GWA]studies in African populations-for example,by reducing the accuracy o genotype imputation in African populations compared to non-African populations".[Lucy Huang etal 2011] Question:Did Henn etal avoid this pitfall in this study of North African Ancestry?What Huang etal is saying is that the high diversity and low Linkage Disequilibrium in African populations must influence the design of GWA studies. [/QB][/QUOTE]
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