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Scientists say an African-American male's odd genetic signature suggests that the human Y chromosome's lineage goes back further in time than they thought — perhaps due to interbreeding with other populations such as Neanderthals....
A photomicrograph shows an X chromosome at left, alongside a shrunken Y chromosome. The Y chromosome is passed down exclusively from father to son and can serve as an indicator of male-line human diversity
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We report the discovery of an African American Y chromosome that carries the ancestral state of all SNPs that defined the basal portion of the Y chromosome phylogenetic tree
Wow. Anybody have the full pdf?
Posts: 318 | Registered: Dec 2004
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^ Interesting find indeed. This finding should put a rest to jumped conclusions about African diversity being the result of 'Eurasian' admixture or Africans suddenly having admixture from archaic hominid species! Posts: 26361 | From: Atlanta, Georgia, USA | Registered: Feb 2005
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There was a request made for the actually .pdf study. Does anyone have access to this?
Posts: 951 | From: where rules end and freedom begins | Registered: Jun 2004
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This is another DNA research which shows how the small sample size and the limited number of ethnic groups in studies can generate false conclusion (here regarding the root of the Y-DNA tree).
In the text, it is mentioned that without the use of a large sampling size of African-Americans, this discovery would never have been made due to small frequency of this new haplogroup in the population.
quote:Given what we know about the coalescent process, the lack of dense sampling in sub-Saharan Africa (especially compared with Europe) has most likely contributed to the failure to identify more cases of incongruence between genealogical and population divergence. The large sample size of African Americans was critical for the discovery of the A00 lineage given its very low frequency estimate in sub-Saharan Africa (0.19% [95% CI ¼ 0.11%–0.35%]).
And they add:
quote:It is likely that a much richer understanding of the Y chromosome phylogeny, as well as of genetic variation in general, would be achieved if more dense and even sampling were to be conducted across sub-Saharan Africa, especially given its high level of genetic diversity.
Considering the high level of genetic diversity in Africa, there's a need for more dense and even sampling in Africa.
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